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Advances in Experimental Medicine and Biology

Stem Cell Biology in Neoplasms of the Central Nervous System

Editors: Ehtesham, Moneeb (Ed.)

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  • Discusses varying hypotheses about CSCs to the overall development of CNS tumors
  • Covers basic neuroscience, translational research aspects, and also includes recent SCS-specific treatment and strategies used in clinical research
  • Appeals to cancer researchers, but also those who are involved in neuro-oncology 
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eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-16537-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-16536-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-3-319-34851-3
  • Free shipping for individuals worldwide
About this book

This volume presents the most current reviews on how cancer stem cells (CSCs) hypothesis dictates that the continued proliferation of a tumor is dependent on a sub-population of self-renewing and asymmetrically dividing neoplastic stem cells that supply a largely differentiated tumor. This volume provides a comprehensive overview of the characteristics of CSCs, their role in central nervous system (CNS) tumors, and the recent CSC-specific treatment modalities being used.
 
The emerging focus on CSCs in brain tumors represents a paradigm shift in our understanding of the pathogenesis of these neoplasms. Importantly, the realization that a distinct sub-population of cells contributes disproportionately to the growth and sustenance of central nervous system tumors has important implications for the treatment of such tumors. To treat CNS tumors, there is now a growing need to treat CSCs to achieve adequate tumor control.

About the authors

Moneeb Ehtesham, M.D. is a Principal Investigator at the Department of Neurological Oncology at Vanderbilt University Medical Center. His research focuses on cellular therapies on malignant gliomas. He has published over 30 peer-reviewed publications, 3 book chapters, and 38 peer-reviewed abstracts/presentations. He has received over 1260 citations. Dr. Ehtesham has been awarded the Young Investigator Award (2003) by the American Association of Neurological Surgeons & Congress of Neurological Surgeons. He's also been listed in "Who's Who in Stem Cell Research" by DataTrend Publications.

Imad Khan, M.D. is a Research Associate at the Geisel School of Medicine at Dartmouth College. His research focuses on therapies for neurosurgical diseases and disorders. He has published over 30 peer-reviewed publications, 3 book chapters, and over 40 peer-reviewed abstracts/presentations.

Reviews

“This is an excellent textbook regarding the molecular and cell biology with respect to brain and spine neoplasms. This is a good book to look at and study if you are interested how cancer comes about. … Research neurologists and neurosurgeons will find the book useful for their animal research. … Graduate students, research fellows, and neuropathologists will be interested in the work presented here.” (Joseph J. Grenier, Amazon.com, August, 2015)


Table of contents (9 chapters)

Table of contents (9 chapters)
  • Regulation of Subventricular Zone-Derived Cells Migration in the Adult Brain

    Pages 1-21

    Capilla-Gonzalez, Vivian (et al.)

  • The SVZ and Its Relationship to Stem Cell Based Neuro-oncogenesis

    Pages 23-32

    Kusne, Yael (et al.)

  • Isolation and Characterization of Stem Cells from Human Central Nervous System Malignancies

    Pages 33-47

    Khan, Imad Saeed, M.D. (et al.)

  • The Role of Stem Cells in Pediatric Central Nervous System Malignancies

    Pages 49-68

    Manoranjan, Branavan (et al.)

  • Laboratory Models for Central Nervous System Tumor Stem Cell Research

    Pages 69-83

    Khan, Imad Saeed, M.D. (et al.)

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-16537-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-16536-3
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: November 18, 2016
  • ISBN 978-3-319-34851-3
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Stem Cell Biology in Neoplasms of the Central Nervous System
Editors
  • Moneeb Ehtesham
Series Title
Advances in Experimental Medicine and Biology
Series Volume
853
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-16537-0
DOI
10.1007/978-3-319-16537-0
Hardcover ISBN
978-3-319-16536-3
Softcover ISBN
978-3-319-34851-3
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XIII, 190
Number of Illustrations
1 b/w illustrations, 15 illustrations in colour
Topics