SpringerBriefs in Computer Science

Protein Homology Detection Through Alignment of Markov Random Fields

Using MRFalign

Authors: Xu, Jinbo, Wang, Sheng, Ma, Jianzhu

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  • Surveys the key topics to aid the reader in quickly learning about this area
  • Presents a novel technique for protein homology search, preparing the reader for future developments
  • Provides an introduction to the software and the web server, enabling the reader to easily make use of the new technique
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eBook $54.99
price for USA in USD
  • ISBN 978-3-319-14914-1
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Softcover $69.99
price for USA in USD
  • ISBN 978-3-319-14913-4
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  • Usually ready to be dispatched within 3 to 5 business days, if in stock
About this book

This work covers sequence-based protein homology detection, a fundamental and challenging bioinformatics problem with a variety of real-world applications. The text first surveys a few popular homology detection methods, such as Position-Specific Scoring Matrix (PSSM) and Hidden Markov Model (HMM) based methods, and then describes a novel Markov Random Fields (MRF) based method developed by the authors. MRF-based methods are much more sensitive than HMM- and PSSM-based methods for remote homolog detection and fold recognition, as MRFs can model long-range residue-residue interaction. The text also describes the installation, usage and result interpretation of programs implementing the MRF-based method.

Table of contents (4 chapters)

Table of contents (4 chapters)

Buy this book

eBook $54.99
price for USA in USD
  • ISBN 978-3-319-14914-1
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $69.99
price for USA in USD
  • ISBN 978-3-319-14913-4
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Protein Homology Detection Through Alignment of Markov Random Fields
Book Subtitle
Using MRFalign
Authors
Series Title
SpringerBriefs in Computer Science
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
The Author(s)
eBook ISBN
978-3-319-14914-1
DOI
10.1007/978-3-319-14914-1
Softcover ISBN
978-3-319-14913-4
Series ISSN
2191-5768
Edition Number
1
Number of Pages
VIII, 51
Number of Illustrations
12 b/w illustrations, 1 illustrations in colour
Topics