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Arterial Disorders

Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

  • Book
  • © 2015

Overview

Editors:
  1. Adel Berbari

    1. American University of Beirut Medical Center, Beirut, Lebanon

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    You can also search for this editor in PubMed   Google Scholar

  2. Giuseppe Mancia

    1. University of Milano Bicocca IRCCS Istituto Auxologico Italiano, Milan, Italy

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    You can also search for this editor in PubMed   Google Scholar

  • Discusses in detail the pathophysiologic mechanisms of arterial disease

  • Explains a range of important novel concepts

  • Covers arterial disease in systemic disorders

  • Explores the role of macrocirculation/microcirculation interaction in target organ damage?

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Table of contents (29 chapters)

  1. Front Matter

    Pages i-ix
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  2. Introductory Aspects

    1. Front Matter

      Pages 1-1
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    2. Definition and Epidemiology of Arterial Disease

      • Reza Aghamohammadzadeh, Danielle Ormandy, Anthony M. Heagerty
      Pages 3-12

    3. Overview of the Normal Structure and Function of the Macrocirculation and Microcirculation

      • Wilmer W. Nichols, Kevin S. Heffernan, Julio A. Chirinos
      Pages 13-46

  3. Classification and Clinical Manifestations of Arterial Disease

    1. Front Matter

      Pages 47-47
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    2. Atherosclerosis

      • Michael Hristov, Christian Weber
      Pages 49-55

    3. Arteriosclerosis/Large Artery Disease

      • Michael F. O’Rourke
      Pages 57-68

    4. Vascular Changes in the Microcirculation: Arterial Remodeling and Capillary Rarefaction

      • Carmine Savoia, Ernesto L. Schiffrin
      Pages 69-79

  4. Pathogenetic Mechanisms in Arterial Disease

    1. Front Matter

      Pages 81-81
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    2. Perinatal Programming of Cardiovascular Disease

      • Maria Franco
      Pages 83-91

    3. Hemodynamic and Mechanical Factors Acting on Arteries

      • Pierre Boutouyrie, Hélène Beaussier, Stéphane Laurent
      Pages 93-99

    4. Role of Metabolic Factors: Lipids, Glucose/Insulin Intolerance

      • Guanghong Jia, Annayya R. Aroor, James R. Sowers
      Pages 101-113

    5. Biomarkers of Vascular Inflammation and Cardiovascular Disease

      • Paul Welsh, David Preiss, Sofia Tsiropoulou, Francisco J. Rios, Adam Harvey, Maria G. Dulak-Lis et al.
      Pages 115-136

    6. Neurohormonal Interactions

      • Gino Seravalle, Guido Grassi
      Pages 137-150

    7. Arterial Interactions with Mineral and Bone Disorders

      • Gérard M. London
      Pages 151-160

    8. Endothelial Function in Health and Disease

      • Arno Greyling, Maria T. Hopman, Dick H. J. Thijssen
      Pages 161-173

    9. Pharmacologic and Environmental Factors: Coffee, Smoking, and Sodium

      • Charalambos Vlachopoulos, Panagiota Pietri, Dimitrios Tousoulis
      Pages 175-186

  5. Systemic Arterial Disorders

    1. Front Matter

      Pages 187-187
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    2. Arterial Ageing

      • Peter M. Nilsson
      Pages 189-202

    3. Renal Arterial Aging

      • Adel E. Berbari, Najla A. Daouk, Samir G. Mallat
      Pages 203-220
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Keywords

About this book

As our knowledge about arterial disease is greatly expanding, the aim of this book is to explore all aspects of arterial pathology, including classification, clinical manifestations, pathogenesis, and therapeutic options. The discussion of pathophysiologic mechanisms of arterial disease is wide ranging, encompassing hemodynamic, metabolic, humoral, inflammatory, genetic and environmental factors. Particular emphasis is placed on recent concepts, such as: the role of age-associated arterial alterations in the initiation and progression of cardiovascular diseases in older persons, the importance of mineral metabolism-bone vascular interactions, the clinical and prognostic significance of the renal resistive index, retinal circulation, toxemia of pregnancy as an arterial disease, and the role of pulmonary/vascular interaction in pulmonary hypertension and cross-talk of macrocirculation and microcirculation in target organ involvement. Evaluation procedures are carefully explained, and the full range of currently available therapeutic options, including lifestyle modifications and pharmacologic approaches, are described and appraised. ​  

Reviews

“This book defines and examines the pathophysiological mechanisms of arterial disorders. … Although intended primarily for general physicians, basic scientists, and physiologists who manage cardiovascular disorders, the book is also useful for internists and medical trainees. … The book includes a comprehensive reference list, color pictures, diagrams, and tables.” (Dustin Y. Yoon, Doody's Book Reviews, May, 2015)

Editors and Affiliations

  • American University of Beirut Medical Center, Beirut, Lebanon

    Adel Berbari

  • University of Milano Bicocca IRCCS Istituto Auxologico Italiano, Milan, Italy

    Giuseppe Mancia

Bibliographic Information

  • Book Title: Arterial Disorders

  • Book Subtitle: Definition, Clinical Manifestations, Mechanisms and Therapeutic Approaches

  • Editors: Adel Berbari, Giuseppe Mancia

  • DOI: https://doi.org/10.1007/978-3-319-14556-3

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer International Publishing Switzerland 2015

  • Hardcover ISBN: 978-3-319-14555-6Published: 31 March 2015

  • Softcover ISBN: 978-3-319-35348-7Published: 08 October 2016

  • eBook ISBN: 978-3-319-14556-3Published: 19 March 2015

  • Edition Number: 1

  • Number of Pages: IX, 431

  • Number of Illustrations: 20 b/w illustrations, 41 illustrations in colour

  • Topics: Cardiology, Angiology, Nephrology, Biomedicine general

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