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Current Topics in Microbiology and Immunology

IgE Antibodies: Generation and Function

Editors: Lafaille, Juan J., Curotto de Lafaille, Maria A. (Eds.)

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  • Summarizes the latest studies on IgE responses
  • Provides valuable insights into the broad spectrum of IgE functions
  • Encourages further studies
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eBook $119.00
price for USA in USD
  • ISBN 978-3-319-13725-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week). Pre-ordered printed titles are excluded from promotions.
  • Due: December 16, 2016
  • ISBN 978-3-319-35888-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Please be advised Covid-19 shipping restrictions apply. Please review prior to ordering
About this book

This volume examines all facets of the complex biology of Immunoglobulin E (IgE) antibodies, which play an essential role in the pathophysiology of allergic diseases and immunity to parasites. It highlights the unique mechanisms involved in the regulation of IgE production at both the molecular and cellular level. Furthermore, it discusses in detail novel findings on how the affinity, specificity and cross-reactivity of IgE can fine-tune mast cell responses to allergens. The book also explores the beneficial roles of IgE antibodies in immunity to helminthes and protection against tumors, and how the properties of IgE-mediated immunity are employed in the development of IgE therapeutic antibodies. All chapters were written by respected experts in their fields and will appeal to scientists and clinicians alike.

Reviews

“This book is a comprehensive, ideal resource for the allergologist, internist/general practitioner, oncologist, pediatrician, as well as the clinical laboratory-based allergologist and immunologist. Reading this book helps us review the basics, recognizing the role of the high affinity IgE receptor and all the surrounding characteristics that shape the allergic response. Most importantly, this book delves into the new applications of IgE-based therapeutics for helminth infections and cancer.” (Paola de Baro-Alvarez, World Allergy Organization WAO, worldallergy.org, April, 2016)


Table of contents (6 chapters)

Table of contents (6 chapters)
  • Biology of IgE Production: IgE Cell Differentiation and the Memory of IgE Responses

    Pages 1-19

    He, Jin-Shu (et al.)

  • Molecular Mechanisms of IgE Class Switch Recombination

    Pages 21-37

    Tong, Pei (et al.)

  • Anti-IgE Therapy: Clinical Utility and Mechanistic Insights

    Pages 39-61

    Logsdon, Stephanie L. (et al.)

  • New Insights on the Signaling and Function of the High-Affinity Receptor for IgE

    Pages 63-90

    Suzuki, Ryo (et al.)

  • Helminth-Induced IgE and Protection Against Allergic Disorders

    Pages 91-108

    Hamid, Firdaus (et al.)

Buy this book

eBook $119.00
price for USA in USD
  • ISBN 978-3-319-13725-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
Softcover $159.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week). Pre-ordered printed titles are excluded from promotions.
  • Due: December 16, 2016
  • ISBN 978-3-319-35888-8
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Please be advised Covid-19 shipping restrictions apply. Please review prior to ordering
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Bibliographic Information

Bibliographic Information
Book Title
IgE Antibodies: Generation and Function
Editors
  • Juan J. Lafaille
  • Maria A. Curotto de Lafaille
Series Title
Current Topics in Microbiology and Immunology
Series Volume
388
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-13725-4
DOI
10.1007/978-3-319-13725-4
Hardcover ISBN
978-3-319-13724-7
Softcover ISBN
978-3-319-35888-8
Series ISSN
0070-217X
Edition Number
1
Number of Pages
IX, 152
Number of Illustrations
5 b/w illustrations, 16 illustrations in colour
Topics