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Mechanical Engineering Series

A Tissue Regeneration Approach to Bone and Cartilage Repair

Editors: Zreiqat, Hala, Dunstan, Colin, Rosen, Vicki (Eds.)

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  • Reviews exhaustively the key recent research regarding bioactive biomaterials and the mechanisms through which they influence the local bone and joint environment to induce tissue repair and regeneration
  • Maximizes reader insights into the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration
  • Demonstrates the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-13266-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-13265-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $149.99
price for USA in USD
  • ISBN 978-3-319-37971-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Reviewing exhaustively the current state of the art of tissue engineering strategies for regenerating bones and joints through the use of biomaterials, growth factors and stem cells, along with an investigation of the interactions between biomaterials, bone cells, growth factors and added stem cells and how together skeletal tissues can be optimised, this book serves to highlight the importance of biomaterials composition, surface topography, architectural and mechanical properties in providing support for tissue regeneration.

Maximizing reader insights into the importance of the interplay of these attributes with bone cells (osteoblasts, osteocytes and osteoclasts) and cartilage cells (chondrocytes), this book also provides a detailed reference as to how key signalling pathways are activated. The contribution of growth factors to drive tissue regeneration and stem cell recruitment is discussed along with a review the potential and challenges of adult or embryonic mesenchymal stem cells to further enhance the formation of new bone and cartilage tissues.

This book serves to demonstrate the interconnectedness of biomaterials, bone/cartilage cells, growth factors and stem cells in determining the regenerative process and thus the clinical outcome.

About the authors

Hala Zreiqat is expert in developing biomaterials for bone/cartilage tissue repair and regeneration and the in vivo/in vitro assessment of cell-biomaterial interaction.

Colin Dunstan is an expert in bone cell biology and the interrelationships between bone cells and their microenvironment.

Vicki Rosen is an expert is studying the physiological roles that bone morphogenetic proteins (BMPs) play in the development, maintenance, and repair of musculoskeletal tissues (bone, cartilage, tendon, ligament, meniscus, muscle).

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Ligand–Receptor Interactions and Their Implications in Delivering Certain Signaling for Bone Regeneration

    Pages 1-15

    Katagiri, Takenobu (et al.)

  • BMPs and Wnts in Bone and Cartilage Regeneration

    Pages 17-37

    Chen, Di (et al.)

  • Osteocytes and Bone Regeneration

    Pages 39-52

    Atkins, Gerald J. (et al.)

  • Skeletal Stem Cells for Bone and Cartilage Tissue Regeneration

    Pages 53-63

    Zaher, Walid (et al.)

  • Manipulation of Macrophages to Enhance Bone Repair and Regeneration

    Pages 65-84

    Nassiri, Sina (et al.)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-319-13266-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-319-13265-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $149.99
price for USA in USD
  • ISBN 978-3-319-37971-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
A Tissue Regeneration Approach to Bone and Cartilage Repair
Editors
  • Hala Zreiqat
  • Colin Dunstan
  • Vicki Rosen
Series Title
Mechanical Engineering Series
Copyright
2015
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-13266-2
DOI
10.1007/978-3-319-13266-2
Hardcover ISBN
978-3-319-13265-5
Softcover ISBN
978-3-319-37971-5
Series ISSN
0941-5122
Edition Number
1
Number of Pages
VI, 254
Number of Illustrations
48 b/w illustrations
Topics