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Transcriptomics in Health and Disease

Editors: Passos, Geraldo A. (Ed.)

  • First book to address transcriptomics in health and disease
  • Written by leading experts in the field
  • Useful for researchers in molecular biology, gene expression, human genetics, immunology, and genomics
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Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-11985-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-3-319-11984-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-35014-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

After sequencing the human genome a decade ago, researchers have continued their projects, but now to try to better understand how, and when, genes are expressed in health and disease. Efforts have been concentrated on the measurement of the expression of RNA transcripts. In an analogy to the genome, the term "transcriptome" was created to refer to the complete set of RNAs in a cell type or tissue in a particular situation. Transcriptomics is the science that studies this issue and it is a branch of functional genomics. Transcriptomics in Heath and Disease provides a comprehensive overview of the science of transcriptomics initially in health, focusing on the concept of the transcriptome and the main methods to evaluate it. The authors discuss the concept and use of gene expression signatures and transcriptional biomarkers in normal development and diseased tissues and organs. As the transcriptome changes depending on the pathology, there is also a focus on the variations in the gene expression in different diseases such as autoimmune, inflammation, cancer and infections. This book should be very useful for researchers in molecular biology focusing on gene expression, human genetics, immunology, and genomics.

Table of contents (17 chapters)

  • What Is the Transcriptome and How it is Evaluated?

    Assis, Amanda F. (et al.)

    Pages 3-48

  • Transcriptome Analysis Throughout RNA-seq

    Raiol, Tainá (et al.)

    Pages 49-68

  • Identification of Biomarkers and Expression Signatures

    Severino, Patricia (et al.)

    Pages 69-78

  • Methods for Gene Coexpression Network Visualization and Analysis

    Moreira-Filho, Carlos Alberto (et al.)

    Pages 79-94

  • Posttranscriptional Control During Stem Cells Differentiation

    Dallagiovanna, Bruno (et al.)

    Pages 95-107

Buy this book

eBook $119.00
price for USA in USD (gross)
  • ISBN 978-3-319-11985-4
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
  • ISBN 978-3-319-11984-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $159.99
price for USA in USD
  • ISBN 978-3-319-35014-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Transcriptomics in Health and Disease
Editors
  • Geraldo A. Passos
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-11985-4
DOI
10.1007/978-3-319-11985-4
Hardcover ISBN
978-3-319-11984-7
Softcover ISBN
978-3-319-35014-1
Edition Number
1
Number of Pages
XVII, 344
Number of Illustrations
10 b/w illustrations, 34 illustrations in colour
Topics