Topics in Medicinal Chemistry

Carbohydrates as Drugs

Editors: Seeberger, Peter H., Rademacher, Christoph (Eds.)

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About this book

Medicinal chemistry is both science and art. The science of medicinal chemistry offers mankind one of its best hopes for improving the quality of life. The art of medicinal chemistry continues to challenge its practitioners with the need for both intuition and experience to discover new drugs. Hence sharing the experience of drug research is uniquely beneficial to the field of medicinal chemistry. Drug research requires interdisciplinary team-work at the interface between chemistry, biology and medicine. Therefore, the topic-related series Topics in Medicinal Chemistry covers all relevant aspects of drug research, e.g. pathobiochemistry of diseases, identification and validation of (emerging) drug targets, structural biology, drugability of targets, drug design approaches, chemogenomics, synthetic chemistry including combinatorial methods, bioorganic chemistry, natural compounds, high-throughput screening, pharmacological in vitro and in vivo investigations, drug-receptor interactions on the molecular level, structure-activity relationships, drug absorption, distribution, metabolism, elimination, toxicology and pharmacogenomics. In general, special volumes are edited by well known guest editors.

Table of contents (8 chapters)

Table of contents (8 chapters)
  • Carbohydrate-Based Synthetic Chemistry in the Context of Drug Design

    Pages 1-21

    Leibeling, Markus (et al.)

  • Iminosugars: Therapeutic Applications and Synthetic Considerations

    Pages 23-51

    Horne, Graeme

  • Computational Docking as a Tool for the Rational Design of Carbohydrate-Based Drugs

    Pages 53-72

    Frank, Martin

  • Discovery and Development of Selective Renal Sodium-Dependent Glucose Cotransporter 2 (SGLT2) Dapagliflozin for the Treatment of Type 2 Diabetes

    Pages 73-94

    Braem, Alan (et al.)

  • Design, Synthesis, and Applications of Galectin Modulators in Human Health

    Pages 95-121

    Mackinnon, Alison (et al.)

Buy this book

eBook $219.00
price for USA in USD
  • ISBN 978-3-319-08675-0
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $299.99
price for USA in USD
Softcover $279.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Carbohydrates as Drugs
Editors
  • Peter H. Seeberger
  • Christoph Rademacher
Series Title
Topics in Medicinal Chemistry
Series Volume
12
Copyright
2014
Publisher
Springer International Publishing
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-319-08675-0
DOI
10.1007/978-3-319-08675-0
Hardcover ISBN
978-3-319-08674-3
Softcover ISBN
978-3-319-34537-6
Series ISSN
1862-2461
Edition Number
1
Number of Pages
VII, 237
Number of Illustrations
68 b/w illustrations, 44 illustrations in colour
Topics