Skip to main content
SpringerLink
Log in
Book cover

Transcriptional Control of Lineage Differentiation in Immune Cells

  • Book
  • © 2014

Overview

Editors:
  1. Wilfried Ellmeier

    1. Medical University of Vienna, Division of Immunobiology, Institute of Immunology, Center of Pathophysiology,Infectiology and Immunology, Vienna, Austria

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  2. Ichiro Taniuchi

    1. RIKEN Center for Integrative Medical Sciences, IMS,, Laboratory for Transcriptional Regulation,, Yokohama, Japan

    View editor publications

    You can also search for this editor in PubMed   Google Scholar

  • Illustrates key transcriptional control mechanisms in immune cells
  • Provides insight into the transcriptional regulatory circuits underlying innate and adaptive immunity
  • Richly illustrated
  • Includes supplementary material: sn.pub/extras

Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 381)

This is a preview of subscription content, log in via an institution to check access.

Access this book

Log in via an institution
eBook USD 129.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Hardcover Book USD 169.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access

Licence this eBook for your library

Institutional subscriptions

Table of contents (10 chapters)

  1. Front Matter

    Pages i-viii
    Download chapter PDF

  2. Genetic and Epigenetic Control of Early Lymphocyte Development

    • Tomokatsu Ikawa
    Pages 1-20

  3. The Role of BTB-Zinc Finger Transcription Factors During T Cell Development and in the Regulation of T Cell-mediated Immunity

    • Wilfried Ellmeier, Ichiro Taniuchi
    Pages 21-49

  4. Transcriptional Control of the Development and Function of Vα14i NKT Cells

    • Isaac Engel, Mitchell Kronenberg
    Pages 51-81

  5. Transcriptional Control of Regulatory T cells

    • Michael Delacher, Lisa Schreiber, David M. Richards, Carla Farah, Markus Feuerer, Jochen Huehn
    Pages 83-124

  6. Transcriptional Regulatory Networks for CD4 T Cell Differentiation

    • Darah Christie, Jinfang Zhu
    Pages 125-172

  7. Transcriptional Control of NK Cell Differentiation and Function

    • Victoria Male, Hugh J. M. Brady
    Pages 173-187

  8. Transcriptional Control of Pre-B Cell Development and Leukemia Prevention

    • Swee Heng Milon Pang, Sebastian Carotta, Stephen L. Nutt
    Pages 189-213

  9. Transcription Factors Controlling Innate Lymphoid Cell Fate Decisions

    • Christoph S. N. Klose, Andreas Diefenbach
    Pages 215-255

  10. Transcriptional Control of Dendritic Cell Differentiation

    • Izumi Sasaki, Tsuneyasu Kaisho
    Pages 257-278

  11. Helper T Cell Plasticity: Impact of Extrinsic and Intrinsic Signals on Transcriptomes and Epigenomes

    • Michael Bonelli, Han-Yu Shih, Kiyoshi Hirahara, Kentner Singelton, Arian Laurence, Amanda Poholek et al.
    Pages 279-326

  12. Back Matter

    Pages 327-331
    Download chapter PDF
Back to top

Keywords

About this book

Insights into the regulation of immune cell lineage differentiation and specification as well as into the control of lineage integrity, stability and plasticity are of fundamental importance to understanding innate and adaptive immune responses. In this volume, leading experts provide an up-to-date and comprehensive overview of recent advances in the transcriptional control mechanisms and transcription factor networks that regulate these processes in a variety of different immune cell lineages. The chapters cover the regulation of T versus B cell lineage choice, discuss early B cell development and pre-B cell leukemia prevention, address transcriptional control mechanisms during the differentiation, in regulatory T cells and iNKT cells, detail genomic switches in helper cell fate choice and plasticity and highlight the role of the BTB-zinc finger family of transcription factors in T cells. Moreover, the chapters discuss transcriptional networks in DCs, NK cells and in innate lymphoid cells. Together, the reviews illustrate key transcriptional control mechanisms that regulate the development and function of immune cells and demonstrate the impressive advances made over the last decade.

Editors and Affiliations

  • Medical University of Vienna, Division of Immunobiology, Institute of Immunology, Center of Pathophysiology,Infectiology and Immunology, Vienna, Austria

    Wilfried Ellmeier

  • RIKEN Center for Integrative Medical Sciences, IMS,, Laboratory for Transcriptional Regulation,, Yokohama, Japan

    Ichiro Taniuchi

About the editors

Wilfried Ellmeier, PhD., is Professor of Immunology at the Institute of Immunology, Center for Pathophysiology, Infectiology and Immunology Medical University of Vienna, Austria. Taniuchi Ichiro, M.D. PhD. Professor is Group Director of the Laboratory for Transcriptional Regulation RIKEN Research Center for Allergy and Immunology (RCAI), Japan.

Bibliographic Information

  • Book Title: Transcriptional Control of Lineage Differentiation in Immune Cells

  • Editors: Wilfried Ellmeier, Ichiro Taniuchi

  • Series Title: Current Topics in Microbiology and Immunology

  • DOI: https://doi.org/10.1007/978-3-319-07395-8

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2014

  • Hardcover ISBN: 978-3-319-07394-1Published: 16 September 2014

  • Softcover ISBN: 978-3-319-37651-6Published: 23 August 2016

  • eBook ISBN: 978-3-319-07395-8Published: 02 September 2014

  • Series ISSN: 0070-217X

  • Series E-ISSN: 2196-9965

  • Edition Number: 1

  • Number of Pages: VIII, 331

  • Topics: Immunology

Publish with us

Policies and ethics

Back to top

Search

Navigation