Journal of Neural Transmission. Supplementa

Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra

Editors: di Giovanni, Giuseppe, Di Matteo, Vincenzo, Esposito, Ennio (Eds.)

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  • Secrets how to "make" a dopaminergic neuron
  • The ID of DA neuron
  • All the possible ways to prevent its death
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eBook $229.00
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  • ISBN 978-3-211-92660-4
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Hardcover $299.99
price for USA in USD
  • ISBN 978-3-211-92659-8
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  • Usually dispatched within 3 to 5 business days.
Softcover $299.99
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  • ISBN 978-3-7091-1092-8
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About this book

This book provides a unique and timely multidisciplinary synthesis of our current knowledge of the anatomy, pharmacology, physiology and pathology of the substantia nigra pars compacta (SNc) dopaminergic neurons. The single chapters, written by top scientists in their fields, explore the life cycle of dopaminergic neurons from their birth to death, the cause of Parkinson's disease, the second most common and disabling condition in the elderly population. Nevertheless, the intracellular cascade of events leading to dopamine cell death is still unknown and, consequently, treatment is symptomatic rather than preventive. The mechanisms by which alterations cause neuronal death, new therapeutic approaches and the latest evidence of a possible de novo neurogenesis in the SNc are reviewed and singled out in different chapters. This book bridges basic science and clinical practice and will prepare the reader for the next few years, which will surely be eventful in terms of the progress of dopamine research.

Table of contents (28 chapters)

Table of contents (28 chapters)
  • Ontogeny of Substantia Nigra Dopamine Neurons

    Orme, R (et al.)

    Pages 3-18

  • Phenotype, Compartmental Organization and Differential Vulnerability of Nigral Dopaminergic Neurons

    González-Hernández, Tomás (et al.)

    Pages 21-37

  • Specific Vulnerability of Substantia Nigra Compacta Neurons

    Smidt, Marten P.

    Pages 39-47

  • The Nigrostriatal Pathway: Axonal Collateralization and Compartmental Specificity

    Prensa, L (et al.)

    Pages 49-58

  • The Localization of Inhibitory Neurotransmitter Receptors on Dopaminergic Neurons of the Human Substantia Nigra

    Waldvogel, HJ (et al.)

    Pages 59-70

Buy this book

eBook $229.00
price for USA in USD (gross)
  • ISBN 978-3-211-92660-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $299.99
price for USA in USD
  • ISBN 978-3-211-92659-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $299.99
price for USA in USD
  • ISBN 978-3-7091-1092-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Birth, Life and Death of Dopaminergic Neurons in the Substantia Nigra
Editors
  • Giuseppe di Giovanni
  • Vincenzo Di Matteo
  • Ennio Esposito
Series Title
Journal of Neural Transmission. Supplementa
Series Volume
73
Copyright
2009
Publisher
Springer-Verlag Wien
Copyright Holder
Springer-Verlag Vienna
eBook ISBN
978-3-211-92660-4
DOI
10.1007/978-3-211-92660-4
Hardcover ISBN
978-3-211-92659-8
Softcover ISBN
978-3-7091-1092-8
Series ISSN
0303-6995
Edition Number
1
Number of Pages
XI, 369
Additional Information
Special edition of Journal of Neural Transmission, Supplement 73
Topics