Metallothionein IV

1. Front Matter

   Pages I-XLVI

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2. Metallothionein nomenclature and structure

   1. Front Matter

      Pages 1-1

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   2. Nomenclature of metallothionein: Proposal for a revision

      • Yutaka Kojima, Pierre-Alain Binz, Jeremias H. R. Kägi

      Pages 3-6

   3. Metallothionein: Molecular evolution and classification

      • Pierre-Alain Binz, Jeremias H. R. Kägi

      Pages 7-13

   4. Structural and biological studies on native bovine Cu,Zn-metallothionein-3

      • Milan Vašák, Ralf Bogumil, Peter Faller, Daniel W. Hasler, Pierre-Alain Binz, Stefan Klauser et al.

      Pages 15-21

   5. Circular dichroism, emission, and exafs studies of Ag(I), Cd(II), Cu(I), and Hg(II) binding to metallothioneins and modeling the metal binding site

      • Martin J. Stillman, Anna Rae Green, Ziqi Gui, David Fowle, P. Anthony Presta

      Pages 23-35

   6. Metallothionein structure update

      • Gülin Öz, Dean L. Pountney, Ian M. Armitage

      Pages 37-43

   7. Simulation of Zn/Cd binding in mammalian metallothionein domains

      • C. C. Chang, P. C. Huang

      Pages 45-49

   8. The growth inhibitory activity of metallothionein-3 correlates with its novel β domain sequence rather than metal binding properties

      • Laran T. Jensen, Jay C. Erickson, Richard D. Palmiter, Dennis R. Winge

      Pages 51-54

   9. Recombinant synthesis and metal-binding abilities of mouse metallothionein 1 and its α- and β-domains

      • Sílvia Atrian, Roger Bofill, Mercè Capdevila, Neus Cols, Pilar González-Duarte, Roser González-Duarte et al.

      Pages 55-61

   10. Biochemical characterization of monomeric and dimeric cadmium-substituted metallothionein-3

       • Peep Palumaa, Rain Lehtme

       Pages 63-69

3. Chemical and analytical aspects of metallothionein

   1. Front Matter

      Pages 71-71

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   2. Mammalian metallothionein sub-isoform separation by RP-HPLC with online UV and electrochemical detection

      • Guy Bordin, Fernando Cordeiro Raposo, Adela Rodriguez

      Pages 73-84

   3. Characterisation of mammalian Cd, Zn metallothioneins using differential pulse polarography

      • Adela Rosa Rodriguez

      Pages 85-91

   4. Comparison of CZE and MECC separations of MT isoforms

      • Vesa Virtanen, Guy Bordin

      Pages 93-97

   5. Synthetic peptides and domains of metallothionein for structure function studies: rabbit liver peptide MT-IIA 49–61 and lobster MT βN βC and βC→N domains

      • Amalia Muñoz, Frank Laib, Eugene DeRose, David H. Petering, John Ejnik, C. Frank Shaw III

      Pages 99-109

   6. Voltammetric methods in isolation and identification of plant metallothioneins from alga Chlorella

      • Ivana Šestáková, Pavel Mader, Hana Vodičková, Vìra Pacáková

      Pages 111-115

   7. Characterization of isometallothioneins in Chang liver cells and the transient accumulation of metallothionein and glutathione during cell proliferation

      • Annemarie Willi, Peter E. Hunziker

      Pages 117-123

   8. Quantification of cytosolic metallothionein contents by a developed assay system using immobilized antibody

      • Tomomi Nagashima, Masashi Okabe, Shigeru Saito, Masaaki Kurasaki, Toshitsugu Hirauchi, Shinzo Kimura et al.

      Pages 125-128

   9. Protein engineering of metallothionein to study the metal-binding ability

      • Masaaki Kurasaki, Futoshi Yamasaki, Rie Yamaguchi, Ana Rosa Linde Arias, Masashi Okabe, Tadasu Emoto et al.

      Pages 129-136

The Proceedings of the Fourth International Metallothionein Meeting (MT-97) feature the latest research on metallothionein. The book covers a broad range of topics which provide important information for both basic and clinical investigators. The selected 94 articles in this book are written by the leading scientists in the field around the world. This is an increasingly important, multi-disciplinary area of study that has benefitted from recent advances in concepts and methodologies from other fields.

• DNA
• apoptosis
• autoimmune disease
• cell culture
• gene expression
• kidney
• metabolism
• mitochondria
• mutation
• protein
• protein engineering
• proteins
• synthesis
• tissue
• transcription

• Medical Center, University of Kansas, Kansas City, USA

  Curtis D. Klaassen

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