Overview
- Editors:
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A. S. H. Ong
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Malaysian Palm Oil Promotion Council, Kuala Lumpur, Malaysia
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L. Packer
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Dept. of Molecular and Cell Biology 251 Life Science Addition, Membrane Bioenergetics Group, Berkeley, USA
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Table of contents (49 chapters)
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Vitamin E: Tocopherols and Tocotrienols and Ubiquinones
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- Cacang Suarna, Roger T. Dean, Roland Stocker
Pages 17-26
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- Girjesh Govil, Ratna S. Phadke, Sudha Srivastava
Pages 27-46
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- Matilde Maiorino, Fulvio Ursini
Pages 47-51
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- Wolf Bors, Christa Michel, Manfred Saran
Pages 52-64
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- I. Tomita, Y. Zhou, M. Ezaki, T. Onda, T. Tomita
Pages 65-75
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- G. G. Duthie, D. B. McPhail, P. C. Morrice, J. R. Arthur
Pages 76-84
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- S. Yukawa, A. Hibino, T. Maeda, H. Nomoto, I. Nishide
Pages 85-91
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- L. Z. Zhu, Y. P. He, J. H. Piao, Q. Y. Cai, C. P. Sun, J. Zh. Chang et al.
Pages 92-104
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- K. C. Hayes, A. Pronczuk, J. S. Liang, S. Lindsey
Pages 105-122
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- Angelo Azzi, Daniel O. Boscoboinik, Eric Chatelain
Pages 123-133
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- J. S. Charnock, T. M. Bridle, J. Turner, P. L. McLennan, M. Y. Abeywardena
Pages 134-151
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- K. Komiyama, M. Hayashi, S. Cha, M. Yamaoka
Pages 152-159
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- Helmut Sies, Michael E. Murphy, Paolo Di Mascio, Wilhelm Stahl
Pages 160-165
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- Michihiro Sugano, Ikuo Ikeda, Katsumi Imaizumi, Kazunori Koba, Takahisa Okamoto, Isao Niiya et al.
Pages 166-177
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Carotenoids, Flavonoids and Retinoids
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- Louise M. Canfield, Jesus G. Valenzuela, John W. Forage
Pages 193-207
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- Hoyoku Nishino, Michiaki Murakoshi, Hirokazu Kitana, Ryozo Iwasaki, Yoshito Tanaka, Miyuki Tsushima et al.
Pages 228-242
About this book
Antioxidants inhibit the formation and spread of free radicals which can be damaging in biological systems. Free radicals form in biological systems through metabolism, but it is also realized that exogenous environmental sources, such as radiation, food, and drugs, contribute significantly to the generation of free radicals in biological systems. Being reactive species, free radicals are short-lived and do not travel far from cellular targets. Their concentration in biological systems is very low and is difficult to detect directly by electron spin resonance spectroscopy (ESR). Indirect methods of reactions of radicals with specific biomolecules are also sufficiently sensitive to detect quantitatively their presence. Thus the response of antioxidant defenses which react with radical species, can serve as an indirect measure that free radicals have been formed. Redox-based antioxidants change their oxidation state and antioxidants become free radicals themselves. Often, however, the antioxidants give rise to more persistent free radicals, sometimes owing to delocalization of the lone electron around ring structures (in vitamin E, ubiquinones, and certain carotenes). Persistent free radicals react only rarely and the precursors often can be regenerated in biological systems. In recent years, it is becoming clearer from biochemical studies on how the major lipophilic antioxidants work. Particular attention has been given to vitamin E and quinones found in animal and plant membranes and in carotenoids, for the protection of membranes in lipoprotein systems. Flavonoids form another rich and varied source of natural antioxidants.
Editors and Affiliations
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Malaysian Palm Oil Promotion Council, Kuala Lumpur, Malaysia
A. S. H. Ong
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Dept. of Molecular and Cell Biology 251 Life Science Addition, Membrane Bioenergetics Group, Berkeley, USA
L. Packer