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Experientia Supplementum

Comparative Molecular Neurobiology

Authors: Pichon, Y.

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About this book

It is generally accepted that all living organisms present on earth derive from one single primordial cell born several billion years ago. One important step in the evolution occurred some 1. 5 billion years ago with the transition from small procaryote cells with relatively simple internal structures such as bacteria to larger and more compleX: eucaryotic cells such as those found in higher animals and plants. Large membrane proteins which enable the cells to communicate appeared early in evolution, and it is believed that the nerve membrane receptors and ionic channels which are observed today in both invertebrate and vertebrate species derive from a common ancestor. Basically, the three identified superfamilies, 1) ionotropic receptors (i. e. receptors containing an integral ionic channel), 2) metabotropic receptors (receptors coupled to G­ proteins) and 3) voltage-dependent ionic channels (Na+, K + and Ca2+ channels) were already well differentiated when vertebrates separated from invertebrate species. The large number of subtypes which are observed in each superfamily may be of more recent evolutionary origin. To understand how this happened, the best approach was to compare the sequences and the properties of the receptors and ionic channels in species sufficiently distant in the evolutionary tree. In the present volume, many of the best specialists in the field of comparative molecular neurobiology, several of them working on vertebrate and invertebrate species, have accepted to report their most recent findings.

Table of contents (22 chapters)

Table of contents (22 chapters)
  • The major lines of metazoan evolution: Summary of traditional evidence and lessons from ribosomal RNA sequence analysis

    Pages 1-30

    Adoutte, André (et al.)

  • Heterologous expression of the membrane proteins that control cellular excitability

    Pages 31-47

    Karschin, Andreas

  • Molluscan ligand-gated ion-channel receptors

    Pages 48-64

    Darlison, Mark G. (et al.)

  • Acetylcholine receptor molecules of the nematode

    Pages 65-80

    Fleming, J. T. (et al.)

  • Acetylcholine receptor/channel molecules of insects

    Pages 81-97

    Leech, C. A. (et al.)

Buy this book

eBook $74.99
price for USA in USD
  • ISBN 978-3-0348-7265-2
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $99.00
price for USA in USD
  • ISBN 978-3-0348-7267-6
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Comparative Molecular Neurobiology
Authors
Series Title
Experientia Supplementum
Series Volume
63
Copyright
1993
Publisher
Birkhäuser Basel
Copyright Holder
Birkhäuser Verlag
eBook ISBN
978-3-0348-7265-2
DOI
10.1007/978-3-0348-7265-2
Softcover ISBN
978-3-0348-7267-6
Series ISSN
1664-431X
Edition Number
1
Number of Pages
X, 436
Topics