Experientia Supplementum

Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance

Editors: Igaz, Peter (Ed.)

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  • Discusses the diagnostic potential of circulating MicroRNAs
  • Presents hypotheses on the potential biological relevance of circulating microRNAs
  • Highlights the role of circulating microRNAs in epigenetics, tumor surveillance and interindvidual communication
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  • ISBN 978-3-0348-0955-9
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Hardcover $169.99
price for USA in USD
  • ISBN 978-3-0348-0953-5
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About this book

MicroRNAs as the endogenous mediators of RNA interference have experienced an unprecedented career in recent years, highlighting their pathogenic, diagnostic and potential therapeutic relevance. Beside tissue microRNAs, they are also found in body fluids, most notably in blood. Significant differences of circulating microRNA levels have been found in various diseases, making them candidates for minimally invasive markers of disease, for example tumor malignancy. The book focuses on the potential diagnostic applicability of circulating microRNAs in various diseases and their potential biological significance.

About the authors

Peter Igaz has degrees in medicine and molecular biology. He works as an associate professor in medicine at Semmelweis University Budapest. He is very actively involved in research focusing on the genomics and bioinformatics of endocrine tumors; the study of microRNAs forms a special focus of his research. His research group was among the first to describe tissue microRNA profiles and microRNA biomarkers of malignancy in adrenocortical and adrenomedullary tumors, and circulating microRNAs in adrenocortical tumor patients. His group developed a novel microRNA target prediction algorithm and analyzed pathways involved in adrenal tumors with bioinformatics tools.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Introduction to microRNAs: Biogenesis, Action, Relevance of Tissue microRNAs in Disease Pathogenesis, Diagnosis and Therapy—The Concept of Circulating microRNAs

    Pages 3-30

    Nagy, Zoltán (et al.)

  • Extracellular microRNAs in Membrane Vesicles and Non-vesicular Carriers

    Pages 31-53

    Coenen-Stass, Anna M. L. (et al.)

  • Technical Aspects Related to the Analysis of Circulating microRNAs

    Pages 55-71

    Butz, Henriett (et al.)

  • Circulating Blood-Borne microRNAs as Biomarkers in Solid Tumors

    Pages 75-122

    Vychytilova-Faltejskova, Petra (et al.)

  • Circulating microRNA as Biomarkers in Hematological Malignancies

    Pages 123-138

    Stankova, Monika (et al.)

Buy this book

eBook $129.00
price for USA in USD
  • ISBN 978-3-0348-0955-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-0348-0953-5
  • Free shipping for individuals worldwide
  • Institutional customers should get in touch with their account manager
  • Covid-19 shipping restrictions & severe weather in the US may cause delays
  • Usually ready to be dispatched within 3 to 5 business days, if in stock
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Bibliographic Information

Bibliographic Information
Book Title
Circulating microRNAs in Disease Diagnostics and their Potential Biological Relevance
Editors
  • Peter Igaz
Series Title
Experientia Supplementum
Series Volume
106
Copyright
2015
Publisher
Springer Basel
Copyright Holder
Springer International Publishing Switzerland
eBook ISBN
978-3-0348-0955-9
DOI
10.1007/978-3-0348-0955-9
Hardcover ISBN
978-3-0348-0953-5
Series ISSN
1664-431X
Edition Number
1
Number of Pages
XII, 288
Number of Illustrations
3 b/w illustrations, 15 illustrations in colour
Topics