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The Biological Role of a Virus

  • Book
  • © 2022

Overview

  • Provides insights into how viruses affect the population diversity of their hosts
  • Describes genetic partnerships between hosts and their viruses
  • Summarizes the most important host defense mechanisms

Part of the book series: Advances in Environmental Microbiology (AEM, volume 9)

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Table of contents (10 chapters)

  1. Viral Control of Community Energetics

  2. Understanding the Genetic Partnership Between a Host and Its Viruses

  3. Defending the Health of Its Hosts

Keywords

About this book

This book answers the question “What is it that viruses do?” by presenting three aspects of viral ecology.

The first aspect explains how viruses affect the population diversity and energetics of their host communities. Perhaps the most notable example of this concept is our understanding that primary production within ecosystems often depends upon those viruses which serve as controllers of nutrient recycling, connecting the aquatic and terrestrial realms in ways that can be assessed locally and globally. 

The second aspect describes genetic partnerships which exist between hosts and their viruses. These include processes termed endogeny and lysogeny by which the host carries at least a partial genomic copy of the virus. Fluidity of these collective genomes is expressed on an evolutionary time scale and the mutual life cycles which they produce represent a forging of shared genomic fate that obligates partnership of the virus and its host. The viral sequences represent a source of potential benefit as well as potential peril for the host and can implement phenotypic changes in the host. Hosts often use those changes as tools. As humans, the most notable example would be that mammals rely upon temporary activation of their endogenous viral genes in order to successfully develop a placenta. 

The third aspect is defending the health of a host, which relies upon activity in two directions. Hosts often use their captured viral genes to identify and subsequently direct battle against invading viruses. This natural concept has been engineered for combating cancer, is useful for suppressing the detrimental consequences of genetic diseases, and has been developed to create targeted antiviral vaccines. But, the defense has to work in two directions and the host can use other symbiotic microorganisms as protection against its viruses.

This book will appeal to a wide readership by providing a broad perspective ofviral ecology, and all scientists will find it helpful for gaining a view of fields beyond their specialization.


Editors and Affiliations

  • Cincinnati, USA

    Christon J. Hurst

About the editor

Christon J. Hurst

Cincinnati, Ohio, USA 

and 

Universidad del Valle, Santiago de Cali, Valle, Colombia

e-mail: christonjhurst@fuse.net

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