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Chondrosarcoma

Biology and Clinical Management

  • A concise, comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas

  • Describes in detail the biology, types and management of chondrosarcoma, with a focus on surgical approaches

  • Excellent for orthopedic oncologists and researchers working with these challenging tumors

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Table of contents (13 chapters)

  1. Front Matter

    Pages i-xvii
  2. Biology of Chondrosarcoma

    1. Front Matter

      Pages 1-1
    2. Pathology of Chondrosarcoma

      • Muhammad Omar Hakim, Andrew Eric Rosenberg
      Pages 3-26
    3. Advances in the Molecular Biology of Chondrosarcoma

      • Zhenfeng Duan, Dylan C. Dean, Susan Bukata, Francis J. Hornicek
      Pages 27-52
    4. Imaging Features of Chondrosarcoma

      • Jonathan Lin, Benjamin D. Levine, Leanne L. Seeger
      Pages 53-73
  3. Skeletal and Extraskeletal Chondrosarcoma

    1. Front Matter

      Pages 75-75
    2. Chondrosarcomas: Conventional and Secondary

      • Christopher M. Hart, Zachary Burke, Alex Nobori, Bennett L. Davis
      Pages 77-91
    3. Primary Soft Tissue Chondrosarcoma

      • Brooke Crawford
      Pages 93-109
  4. Management of Chondrosarcoma

    1. Front Matter

      Pages 111-111
    2. Chondrosarcoma of the Axial Skeleton

      • Akash A. Shah, Howard Young Park, Gideon Blumstein, Don Young Park
      Pages 113-132
    3. Chondrosarcoma of the Appendicular Skeleton

      • Erik J. Geiger, Nicholas M. Bernthal
      Pages 133-167
    4. Chondrosarcoma of the Hand

      • Karren Takamura, Neil Ford Jones
      Pages 169-186
    5. Chondrosarcoma of the Clavicle

      • Tang Liu, Chao Tu, Zhihong Li
      Pages 187-202
    6. Radiation Therapy for Chondrosarcoma

      • Ting Martin Ma, Thomas DeLaney, Anusha Kalbasi
      Pages 203-253
    7. Systemic Therapy for Chondrosarcoma

      • Arun S. Singh, Jomjit Chantharasamee, Francis J. Hornicek
      Pages 255-268
    8. Vascular Issues in Complex Surgical Resection of Chondrosarcoma

      • Rhusheet Patel, Donald T. Baril
      Pages 269-279
  5. The Future of Chondrosarcoma Research and Treatment

    1. Front Matter

      Pages 281-281
    2. The Future of Chondrosarcoma Research and Treatment

      • Pichaya Thanindratarn, Dylan C. Dean, Francis J. Hornicek, Zhenfeng Duan
      Pages 283-298
  6. Back Matter

    Pages 299-304

About this book

Chondrosarcoma, a rare cancer that develops from cartilage cells, occurs mainly in the bones but can also appear in the soft tissue of the pelvis, hip and shoulder. Unfortunately, these cancers are highly resistant to both chemotherapy and radiation, and no successful adjuvant therapies currently exist. As such, surgical treatment and resection remain the mainstays of management for patients with these tumors.

This concise text is a comprehensive presentation of the current knowledge regarding the development, diagnosis and management of chondrosarcomas. Part I discusses pathology, molecular biology and imaging features of chondrosarcomas. The different types of skeletal and extraskeletal tumors are presented in detail in part II, including conventional and secondary tumors. Management approaches are outlined and described in part III - limb salvage surgery is the most common, and although less effective, radiation and chemotherapy are indicated in certain cases. Part IV examines the future of chondrosarcoma management and development of novel adjuvant therapies, as well as the relationship of this disease to similar types (e.g., chordoma).

 Bringing together the most up-to-date information on this rare cancer, Chondrosarcoma will be a valuable resource for orthopedic oncologists, researchers and all medical professionals treating these challenging tumors. 


Editors and Affiliations

  • Department of Orthopaedic Surgery, David Geffen School of Medicine at UCLA, Los Angeles, USA

    Francis J. Hornicek

About the editor



Francis John Hornicek, M.D., Ph.D.

Professor and Chair

Department of Orthopaedic Surgery

Helga and Walter Oppenheimer Endowed Chair in Orthopaedic Oncology

David Geffen School of Medicine at UCLA

10833 Le Conte Ave, 76-143 CHS

Los Angeles, CA 



Bibliographic Information

  • Book Title: Chondrosarcoma

  • Book Subtitle: Biology and Clinical Management

  • Editors: Francis J. Hornicek

  • DOI: https://doi.org/10.1007/978-3-030-74572-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2021

  • Softcover ISBN: 978-3-030-74571-4Published: 18 June 2021

  • eBook ISBN: 978-3-030-74572-1Published: 17 June 2021

  • Edition Number: 1

  • Number of Pages: XVII, 304

  • Number of Illustrations: 29 b/w illustrations, 35 illustrations in colour

  • Topics: Orthopedics, Oncology

Buy it now

Buying options

eBook USD 64.99
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 84.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access