Editors:
- Presents state-of-the-art reviews of key issues relating to chronic myeloid leukemia
- Covers a wide range of management topics
- Discusses prognostic aspects and early response prediction
- Examines the changing face and cost of care
Part of the book series: Hematologic Malignancies (HEMATOLOGIC)
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Table of contents (16 chapters)
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Front Matter
About this book
This book provides state-of-the-art reviews of key issues and recent developments relating to chronic myeloid leukemia (CML), acquainting the reader with advances in research, treatment, and promotion of public health. Among the management topics addressed are the choices, advantages, and pitfalls of first-, second-, and third-line treatments; the European LeukemiaNet recommendations; management of adverse effects of tyrosine kinase inhibitors (TKI); management of CML blast crisis; management of pregnancy in the context of CML; the role of hematopoietic cell transplantation; the current experience with TKI discontinuation; and the value of interferon α in improving the outcome of TKI treatment. Various aspects of relevance to treatment outcome are discussed, including prognostic scores, molecular monitoring (principles and interlaboratory standardization), and response-related predictors of survival. Furthermore, updates are provided on the increasing prevalence of CML and its implications and on the changing cost of care for CML, taking into account the impact of availability of generic imatinib.
Editors and Affiliations
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ELN Foundation, Weinheim, Germany
Rüdiger Hehlmann
About the editor
Rüdiger Hehlmann is a Professor of Medicine at the Mannheim Medical Faculty of the University of Heidelberg, Germany.
Founder and Chair, European LeukemiaNet (ELN)
Founder and chair of the German CML Study Group 1982-2017
Former Secretary General
International Association of Comparative Research on Leukemia & Related Diseases (IACRLRD)
Former Chief of Medicine, Dean & President
German Society of Hematology and Oncology
Honorary member of the Polish and German Societies for Hematology and Oncology
Current focus: promotion of cooperative research for curing leukemia
Bibliographic Information
Book Title: Chronic Myeloid Leukemia
Editors: Rüdiger Hehlmann
Series Title: Hematologic Malignancies
DOI: https://doi.org/10.1007/978-3-030-71913-5
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2021
Hardcover ISBN: 978-3-030-71912-8Published: 03 June 2021
Softcover ISBN: 978-3-030-71915-9Published: 04 June 2022
eBook ISBN: 978-3-030-71913-5Published: 02 June 2021
Series ISSN: 2197-9766
Series E-ISSN: 2197-9774
Edition Number: 2
Number of Pages: IX, 273
Number of Illustrations: 7 b/w illustrations, 35 illustrations in colour
Topics: Oncology, Hematology