Microbial Pathogenesis

1. Front Matter

   Pages i-xiii

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2. Human Papillomavirus-Associated Cancers

   • Fatimah S. Alhamlan, Mohamed B. Alfageeh, Mona A. Al Mushait, Ismail A. Al-Badawi, Mohammed N. Al-Ahdal

   Pages 1-14

3. Mechanisms of Immune Evasion by Ebola Virus

   • Suchita Bhattacharyya

   Pages 15-22

4. Innate Immune Response Against HIV-1

   • Valarmathy Murugaiah, Hadida Yasmin, Hrishikesh Pandit, Kasturi Ganguly, Rambhadur Subedi, Maha Al-Mozaini et al.

   Pages 23-58

5. Current Insights into the Host Immune Response to Respiratory Viral Infections

   • Kumari Asha, Madhu Khanna, Binod Kumar

   Pages 59-83

6. Immune Responses to MERS-CoV in Humans and Animals

   • Naif Khalaf Alharbi, Swarali S. Kulkarni, Darryl Falzarano

   Pages 85-97

7. SARS-CoV-2: Pathogenic Mechanisms and Host Immune Response

   • Hadida Yasmin, Sudipta Saha, Mariam Tariq Butt, Rishab Kumar Modi, Andrew J. T. George, Uday Kishore

   Pages 99-134

8. Antibiotic Resistance Mechanisms and Their Transmission in Acinetobacter baumannii

   • Ronan R. McCarthy, Gerald J. Larrouy-Maumus, Mei Gei C. Meiqi Tan, David W. Wareham

   Pages 135-153

9. Pathogenesis and Host Immune Response in Leprosy

   • Hadida Yasmin, Praveen Mathews Varghese, Sanjib Bhakta, Uday Kishore

   Pages 155-177

10. Innate Immune Pattern Recognition Receptors of Mycobacterium tuberculosis: Nature and Consequences for Pathogenesis of Tuberculosis

    • Anthony G. Tsolaki, Praveen Mathews Varghese, Uday Kishore

    Pages 179-215

11. Vaccination Strategies Against Mycobacterium tuberculosis: BCG and Beyond

    • Janez Ferluga, Hadida Yasmin, Sanjib Bhakta, Uday Kishore

    Pages 217-240

12. Candida Pathogenicity and Interplay with the Immune System

    • Nisha Valand, Umakhanth Venkatraman Girija

    Pages 241-272

13. Immune Responses in Malaria and Vaccine Strategies

    • Janez Ferluga, Iesha Singh, Sashmita Rout, Ahmed Al-Qahtani, Hadida Yasmin, Uday Kishore

    Pages 273-291

This book updates in detail the microbial pathogenesis of various important pathogens, including HIV-1, MERS, SARS-CoV-2, Mycobacterium and Plasmodium. There is also a general discussion of the innate and adaptive immune responses against primary and opportunistic infections. The overall purpose of the book is to aid in the development of anti-viral and anti-microbial targets.

• pathogen
• vaccine
• virus
• tuberculosis
• disease

• Biosciences, College of Health, Medicine and Life Sciences, Brunel University, London, UK

  Uday Kishore

Uday Kishore is a teacher and a scientist with special interest in innate immunity. He was the Founder Director of the Centre for Infection, Immunity and Disease Mechanisms, Brunel University London. He earned his BSc from S.P. Jain College, Sasaram, Bihar, India; MSc from Hindu College, Delhi; and PhD from the Department of Zoology, University of Delhi and CSIR Institute of Genomics and Integrative Biology, Delhi, India. After spending a year at the Salk Institute for Biological Studies, La Jolla, California, he moved to the University of Oxford for the major part of his post-doctoral training, first at the MRC Immunochemistry Unit, Department of Biochemistry, and then at the Weatherall Institute of Molecular Medicine, John Radcliffe Hospital. His is the recipient of fellowships of NASA (USA), Wellcome Trust (UK) and Alexander Humboldt Foundation (Germany), MRC Investigator Prize, European Commission Young Scientist Prize, and Mother Teresa Excellence Award. Uday Kishore holds severaladjunct, visiting and honorary professorial positions nationally and internationally. He has altogether authored over 200 research papers, book chapters, patents, and books. His research focuses on how C-type lectins (especially collectins such as surfactant protein D) and individual complement proteins (C1q, factor H and properdin) resist a range of pathogens such as HIV-1, SARS-CoV-2, Influenza A Virus, Mycobacterium tuberculosis, Aspergillus fumigatus and Plasmodium falciparum.

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