Environmental Contaminants and Neurological Disorders

1. Front Matter

   Pages i-xii

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2. Pathogenesis of Neurodegeneration and Associated Neurological Disorders

   • Tauqeer Hussain Mallhi, Amna Saifullah, Yusra Habib Khan, Amjad Khan, Nasser Hadal Alotaibi, Abdulaziz Ibrahim Alzarea

   Pages 1-30

3. Air Pollutants and Neurological Disorders: From Exposure to Preventive Interventions

   • Tauqeer Hussain Mallhi, Muhammad Hammad Butt, Abrar Ahmad, Shahzadi Misbah, Suleman Atique, Yusra Habib Khan

   Pages 31-47

4. Bacterial Endotoxins and Neurological Disorders: From Exposure to Therapeutic Interventions

   • Yusra Habib Khan, Aroosa Liaqat, Tauqeer Hussain Mallhi, Arooj Abid, Nasser Hadal Alotaibi, Amjad Khan

   Pages 49-67

5. Heavy Metals and Neurological Disorders: From Exposure to Preventive Interventions

   • Qudsia Rehman, Kanwal Rehman, Muhammad Sajid Hamid Akash

   Pages 69-87

6. Pesticides and Neurological Disorders: From Exposure to Preventive Interventions

   • Sumera Qasim, Yusra Habib Khan, Tauqeer Hussain Mallhi

   Pages 89-109

7. Cigarette Smoking and Neurological Disorders: From Exposure to Therapeutic Interventions

   • Yusra Habib Khan, Arooj Abid, Aroosa Liaqat, Muhammad Hammad Butt, Abrar Ahmad, Shahzadi Misbah et al.

   Pages 111-124

8. Mechanistic Insight of Mycotoxin-Induced Neurological Disorders and Treatment Strategies

   • Zunera Chauhdary, Kanwal Rehman, Muhammad Sajid Hamid Akash

   Pages 125-146

9. Polycarbonate Plastics and Neurological Disorders: From Exposure to Preventive Interventions

   • Zubair Anwar, Fakhsheena Anjum, Sana Ghayas

   Pages 147-183

10. Bisphenol A and Neurological Disorders: From Exposure to Preventive Interventions

    • Muhammad Sajid Hamid Akash, Muhammad Ejaz ul Haq, Hina Sharif, Kanwal Rehman

    Pages 185-200

11. Volatile Organic Compounds and Neurological Disorders: From Exposure to Preventive Interventions

    • Amjad Khan, Hafsa Kanwal, Salma Bibi, Saima Mushtaq, Arshad Khan, Yusra Habib Khan et al.

    Pages 201-230

12. Persistent Organic Pollutants and Neurological Disorders: From Exposure to Preventive Interventions

    • Hammad Ahmed, Ali Sharif, Sahar Bakht, Faraza Javed, Waseem Hassan

    Pages 231-247

13. Polychlorinated Biphenyls and Neurological Disorders: From Exposure to Preventive Interventions

    • Mutayyba Fatima, Kanwal Rehman, Muhammad Sajid Hamid Akash

    Pages 249-280

14. Phthalates and Neurological Disorders: From Exposure to Preventive Interventions

    • Asma Ashraf, Shumaila Kiran, Saima Muzammil, Sumreen Hayat, Muhammad Umar Ijaz, Aqsa Muzammil

    Pages 281-307

15. Perfluoroalkyl Chemicals and Neurological Disorders: From Exposure to Preventive Interventions

    • Samia Gul Niazi, Chanda Javed, Taiba Suleman, Samra Sadiq, Imtiaz Mahmood Tahir

    Pages 309-334

16. Polycyclic Aromatic Hydrocarbons and Neurological Disorders: From Exposure to Preventive Interventions

    • Ajab Khan, Ali Raza Jahego

    Pages 335-353

17. Nanomaterials as Source of Environmental Contaminants: From Exposure to Preventive Interventions

    • Shagufta Kamal, Muhammad Junaid, Ismat Bibi, Amna Kamal, Kanwal Rehman, Muhammad Sajid Hamid Akash

    Pages 355-400

18. Back Matter

    Pages 401-410

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This volume discusses how environmental pollutants are involved in the pathogenesis of neurological disorders, and covers specific mechanisms and risk factors, as well as the necessary strategies to reduce the adverse impacts of environmental pollutants on the human nervous system. With a collection of contributions from experts in environmental pollution, neurology and pharmaceutical chemistry, the book provides both an introduction to the pathogenesis of neurodegeneration, including the types and different classes of neurological disorders, and studies demonstrating the clear link between environmental contaminants (e.g. pesticides, smoking, mycotoxins, persistent organic pollutants (POP's), polychlorinated biphenyls, phthalates, nanomaterials) and the development of neurological disorders in vulnerable populations. The book fills in a gap in research on the topic by also covering state-of-the-art treatment strategies and mitigation measures for each type of pollutant. The book will be of interest to environmental scientists, pharmacologists, toxicologists, biochemists, biotechnologists, and food and drug regulatory organizations.

• Pharmaceutical chemistry
• Neurodegeneration
• Air pollution
• Neurological disorders
• Mycotoxins
• Persistent organic pollutants
• Phthalates
• Environmental contaminants

• Department of Pharmaceutical Chemistry, Government College University, Faisalabad, Pakistan

  Muhammad Sajid Hamid Akash

• Department of Pharmacy, University of Agriculture, Faisalabad, Pakistan

  Kanwal Rehman

Dr. Muhammad Sajid Hamid Akash (PAS Gold Medal) is an Associate Professor and Chair of the Department of Pharmaceutical Chemistry at Government College University, Faisalabad, Pakistan. Dr. Akash works on the impact of contaminates and disruptors on various molecular pathways that are involved in cardiometabolic and neurological disorders.

Dr. Kanwal Rehman is an Assistant Professor in the Department of Pharmacy, at the University of Agriculture, Faisalabad, Pakistan. She is focusing on the investigation of role of pharmacogenomics based upon gene polymorphism on various molecular and metabolic pathways that are involved in mitogenic disorders and treatment strategies using natural biogenic compounds, secondary metabolites against different risk factors of metabolic disorders.

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