Editors:
Written in a handbook format with clinical tips for a variety of medical professionals
Discusses epidemiology, clinical manifestations, diagnosis, differential diagnosis, and treatment of rheumatic irAE
Includes management algorithms for arthritis, myositis, polymyalgia rheumatica, and Sjogren’s syndrome
Addresses cancer immunotherapy in patients with preexisting rheumatic diseases
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Table of contents (16 chapters)
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Front Matter
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Immune-Related Adverse Events with Immune-Checkpoint Inhibitors
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Front Matter
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Cancer Immunotherapy in Patients with Pre-existing Rheumatic Diseases
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Front Matter
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General Principles of Management
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Front Matter
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About this book
With the increasing use of immune checkpoint inhibitors (ICI) across various cancers, the trends for indication at earlier stages, and the use of combination immunotherapy, the frequency of ICI-induced immune-related adverse events (irAE) is expected to grow substantially. Management of these irAE is challenging as it requires not only consideration of the toxicity but also risk-benefit ratios with respect to the primary cancer. Several rheumatic irAE have been reported with ICI therapy including arthritis, myositis, polymyalgia-like syndromes, sicca/Sjogren-like manifestations, and several other less common systemic autoimmune features commonly associated with connective tissue disease.
Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy is an essential resource for physicians and related professionals, residents, fellows, graduate students and nurses alike in rheumatology, clinical immunology, oncology, and internal medicine.
Keywords
- Cancer immunotherapy and rheumatic diseases
- Cancer immunotherapy and arthritis
- Cancer immunotherapy and myositis
- Cancer immunotherapy and polymyalgia rheumatic
- Cancer immunotherapy and Sjogren’s syndrome
- Cancer immunotherapy-induced rheumatic diseases
- Immune checkpoint inhibitors (ICI)
- Rheumatic immune-related adverse events (irAE)
Editors and Affiliations
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Department of Health Services Research, University of Texas MD Anderson Cancer Center, Houston, USA
Maria E. Suarez-Almazor
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Department of Rheumatic and Immunologic Diseases, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University, Cleveland, USA
Leonard H. Calabrese
About the editors
Maria E. Suarez-Almazor, MD, PhD.
Barnts Family Professor
Departments of Health Services Research and General Internal Medicine, Section of Rheumatology and Clinical Immunology
The University of Texas MD Anderson Cancer Center
FCT 9.5026
1400 Pressler St (Unit 1444)
Houston, TX, 77030msalmazor@mdanderson.org
Leonard H. Calabrese, D.O.
Professor of Medicine,
Cleveland Clinic Lerner College of Medicine
RJ Fasenmyer Chair of Clinical Immunology
Vice Chairman, Department of Rheumatic and Immunologic Diseases
College of Medicine of Case Western Reserve University
9500 Euclid Avenue, Desk A50
Cleveland, Ohio 44195
CALABRL@ccf.org
Bibliographic Information
Book Title: Rheumatic Diseases and Syndromes Induced by Cancer Immunotherapy
Book Subtitle: A Handbook for Diagnosis and Management
Editors: Maria E. Suarez-Almazor, Leonard H. Calabrese
DOI: https://doi.org/10.1007/978-3-030-56824-5
Publisher: Springer Cham
eBook Packages: Medicine, Medicine (R0)
Copyright Information: Springer Nature Switzerland AG 2021
Softcover ISBN: 978-3-030-56823-8Published: 17 February 2021
eBook ISBN: 978-3-030-56824-5Published: 16 February 2021
Edition Number: 1
Number of Pages: XIV, 363
Number of Illustrations: 3 b/w illustrations, 16 illustrations in colour
Topics: Rheumatology, Oncology, Immunology