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Advances in Experimental Medicine and Biology

Notch Signaling in Embryology and Cancer

Notch Signaling in Cancer

Editors: Reichrath, Jörg, Reichrath, Sandra (Eds.)

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  • The content is presented in a logical and coherent structure, enabling the reader to readily access relevant information
  • The volume editors are renowned experts on Notch and Notch Signaling and the chapter contributors are all internationally-recognized researchers
  • Timely and urgently needed update in a rapidly moving field
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eBook $149.00
price for USA in USD
  • ISBN 978-3-030-55031-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
About this book

This thoroughly revised second edition is an up-to-date overview of the current knowledge of Notch and Notch signaling in embryology and cancer. It discusses this topic from Notch’s role in the development of the embryo to the Notch signaling pathway’s role in the development of a number of cancers, including breast cancer, malignant melanoma, Non-melanoma skin cancer, intestinal cancer and others. In the years since the previous edition, there have been numerous developments and insights within this rapidly moving field, making this new edition urgently needed. This volume also features discussions of current insights on Notch’s role in senescence, the regulation of Notch signaling by microRNAs, Notch’s role in the microbiome, diet and its influence on Notch signaling and more.

Taken as a whole, with its companion books -- Notch Signaling and Embryologic Development and Molecular Basis of Notch Signaling – this is a definitive discussion of the topic, presented by internationally-recognized contributors.  Presented in a coherent and accessible structure, this revised and updated second edition is an essential and up-to-date guide for oncologists, embryologists, researchers and advanced students.

About the authors

Jörg Reichrath is Professor for Dermatology and Deputy Director of the Clinic for Dermatology, Allergology and Venerology at the Saarland University Medical Center in Homburg, Germany. Reichrath has received his academic degrees (Dr. med.) from the Saarland University, Germany. His research interests include photobiology, dermato-endocrinology and dermato-oncology. He is a member of numerous national and international scientific organizations, including the German Dermatological Society (DDG), the Deutsche Krebsgesellschaft (DKG), the German Dermatologic Cooperative Oncology Group (DeCOG), the Arbeitsgemeinschaft Dermatologische Forschung (ADF) and the Deutsche Akademie für Photobiologie und Phototechnologie e. V. (DAFP). He has been awarded numerous prices including the Arnold-Rikli-price.

 

Sandra Reichrath is researcher and scientist at the Clinic for Dermatology, Allergology and Venerology at the Saarland University Medical Center Hospital in Homberg, Germany, where she at present works at the School of Health Professions. She received her academic degrees from the Faculty of Biology of the Albert-Ludwig-University, Freiburg, Germany. Her research interests include Notch signaling in glioblastoma and skin tumors.

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Notch Signaling in Prevention And Therapy: Fighting Cancer with a Two-Sided Sword

    Pages 1-7

    Reichrath, Jörg (et al.)

  • Transcription Factor RBPJ as a Molecular Switch in Regulating the Notch Response

    Pages 9-30

    Giaimo, Benedetto Daniele (et al.)

  • Unravelling of Hidden Secrets: The Tumour Suppressor Lethal (2) Giant Discs (Lgd)/CC2D1, Notch Signalling and Cancer

    Pages 31-46

    Reiff, Tobias (et al.)

  • Notch and Endometrial Cancer

    Pages 47-57

    Jonusiene, Violeta (et al.)

  • NOTCH and Esophageal Squamous Cell Carcinoma

    Pages 59-68

    Li, Yong (et al.)

Buy this book

eBook $149.00
price for USA in USD
  • ISBN 978-3-030-55031-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $199.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Notch Signaling in Embryology and Cancer
Book Subtitle
Notch Signaling in Cancer
Editors
  • Jörg Reichrath
  • Sandra Reichrath
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1287
Copyright
2021
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-55031-8
DOI
10.1007/978-3-030-55031-8
Hardcover ISBN
978-3-030-55030-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
XVII, 228
Number of Illustrations
1 b/w illustrations, 27 illustrations in colour
Topics