Overview
Updated, state-of-the-art information that is clinically and scientifically valuable for physicians, investigators, and students
Comprehensive overview that is relevant to practitioners in multiple specialties
Developed by an international panel of renowned experts
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Table of contents (36 chapters)
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Front Matter
Keywords
About this book
The third edition of this acclaimed work provides clinicians and investigators with a wealth of state-of-the-art information that will lead to fresh approaches in thinking about liver physiology and liver diseases. Developed by a panel of renowned international authors, this edition outlines a range of important advances in our understanding of the liver’s role as an immune organ and the functions of innate and adaptive immunity in the pathogenesis of all liver diseases. Indeed, the liver is a vitally important immune organ producing liver-derived products that can trigger the innate and adaptive immune system to initiate, mediate, regulate, and resolve systemic inflammation.
The book begins with an analysis of the core concepts of immunology, including the definition of autoimmunity and its unique application to the liver, a tolerogenic organ. Subsequent chapters then explore the biological elements of liver diseases caused by epigenetics, genetics, and innate and adaptive immunity. Specific clinical presentations and aspects of liver diseases are also examined, such as Hepatitis C, non-alcoholic fatty liver disease and parasitic infections. Closing chapters then discuss liver diseases among specific populations, including pediatrics, those with comorbidities and preexisting conditions, pregnant women, and finally patients with transplanted organs.
A timely and invaluable update to the clinical literature, Liver Immunology: Principles and Practice, Third Edition, is once again a comprehensive work that will not only enhance the understanding of liver diseases but also provide the kind of novel insights that greatly accelerates the evidence-based care of children and adults afflicted with these diseases. This volume is again a must-read for clinicians at all levels, for investigators and for students.
Editors and Affiliations
About the editors
M. Eric Gershwin, MD
Distinguished Professor of Medicine
The Jack and Donald Chia Endowed Professor
University of California School of MedicineDavis, CA
USA
John M. Vierling, MD
Professor of Medicine and Surgery
Chief of Hepatology
Director of Baylor Liver Health
Baylor College of Medicine
Houston, TX
USA
Atsushi Tanaka, MD, PhD
Professor
Department of Medicine
Teikyo University School of Medicine
Tokyo, Japan
Michael P. Manns, MD
Professor and Department of Medicine Chair
Department of Gastroenterology, Hepatology, and Endocrinology
Hannover Medical SchoolHannover, Germany
Bibliographic Information
Book Title: Liver Immunology
Book Subtitle: Principles and Practice
Editors: M. Eric Gershwin, John M. Vierling, Atsushi Tanaka, Michael P. Manns
DOI: https://doi.org/10.1007/978-3-030-51709-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-51708-3Published: 04 November 2020
Softcover ISBN: 978-3-030-51711-3Published: 05 November 2021
eBook ISBN: 978-3-030-51709-0Published: 03 November 2020
Edition Number: 3
Number of Pages: XV, 633
Number of Illustrations: 10 b/w illustrations, 135 illustrations in colour
Topics: Immunology