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Cellular Nanomachines

From Discovery to Structure-Function and Therapeutic Applications

Authors: Jena, Bhanu P.

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  • Illustrates the structure, isolation, composition, and the functional reconstitution of the porosomes nanomachine: cells’ secretory portal
  • Describes diseases targeting proteasomes, as well as diseases resulting from altered chaperonin, porosome, and ATP synthase
  • Provides readers with an overview of the possible mechanisms involved in the assembly of cellular nanomachines
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  • ISBN 978-3-030-44496-9
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About this book

In this book, the major paradigm-shifting discoveries made in the past century on key cellular nanomachines are described in great detail: their complex yet precise and elegant design and function, as well as the diseases linked to their dysfunction and the therapeutic approaches to overcome them. The major focus of this book is the “porosome” nanomachine, the universal secretory portal in cells. This is an ideal book for students, researchers, and professionals in the fields of nanoscience and nanotechnology.

About the authors

Bhanu P. Jena is George E. Palade University Professor & Distinguished Professor of Physiology at Wayne State University School of Medicine, and Director of the NanoBioScience Institute. In 1996 while an Assistant Professor at Yale University School of Medicine, he discovered the ‘porosome’, a new cellular nanomachine that serves as the secretory portal in cells. Prof. Jena is the recipient of numerous awards and honours, among them six honorary doctorates, the Aaron Klug Award, Palade Gold Medal, and AAAS Fellow. He received his Ph.D. from Iowa State University followed by postdoctoral training as a Swebilius Fellow at Yale University. 

Table of contents (8 chapters)

Table of contents (8 chapters)

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-030-44496-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-030-44495-2
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Cellular Nanomachines
Book Subtitle
From Discovery to Structure-Function and Therapeutic Applications
Authors
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-44496-9
DOI
10.1007/978-3-030-44496-9
Hardcover ISBN
978-3-030-44495-2
Edition Number
1
Number of Pages
XVIII, 109
Number of Illustrations
1 b/w illustrations, 40 illustrations in colour
Topics

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