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Concepts and Applications of Stem Cell Biology

A Guide for Students

  • Textbook
  • © 2020

Overview

Editors:
  1. Gabriela Rodrigues

    1. Centro de Ecologia, Evolução e Alterações Ambientais, Departamento de Biologia Animal, Faculdade de Ciências da, Universidade de Lisboa, Lisbon, Portugal

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  2. Bernard A. J. Roelen

    1. Embryology, Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht Universtity, Utrecht, The Netherlands

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  • It provides a detailed and updated view on stem cell biology
  • It offers basic understanding on early development and primordial germ cells
  • It discusses neural and cardiac regeneration
  • It describes the diverse biomedical applications of stem cells

Part of the book series: Learning Materials in Biosciences (LMB)

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Table of contents (14 chapters)

  1. Front Matter

    Pages I-XXII
    Download chapter PDF

  2. Introduction: A Decade Teaching Stem Cell Biology

    • Gabriela Rodrigues
    Pages 1-9

  3. Preimplantation Development: From Germ Cells to Blastocyst

    • Bernard A. J. Roelen
    Pages 11-27

  4. Origins of Pluripotency: From Stem Cells to Germ Cells

    • Maria Gomes Fernandes, Susana M. Chuva de Sousa Lopes
    Pages 29-55

  5. Human Induced Pluripotent Stem (hiPS) Cells: Generation and Applications

    • Christian Freund
    Pages 57-71

  6. Cellular Reprogramming and Aging

    • Sandrina Nóbrega-Pereira, Bruno Bernardes de Jesus
    Pages 73-91

  7. Cloning

    • Bernard A. J. Roelen
    Pages 93-113

  8. Stem Cells in Plant Development

    • Beatriz Gonçalves
    Pages 115-130

  9. Axial Stem Cells and the Formation of the Vertebrate Body

    • André Dias, Rita Aires
    Pages 131-158

  10. Skeletal Muscle Development: From Stem Cells to Body Movement

    • Marianne Deries, André B. Gonçalves, Sólveig Thorsteinsdóttir
    Pages 159-185

  11. Cardiac Regeneration and Repair: From Mechanisms to Therapeutic Strategies

    • Vasco Sampaio-Pinto, Ana C. Silva, Perpétua Pinto-do-Ó, Diana S. Nascimento
    Pages 187-211

  12. Reproducing Human Brain Development In Vitro: Generating Cerebellar Neurons for Modelling Cerebellar Ataxias

    • Evguenia Bekman, Teresa P. Silva, João P. Cotovio, Rita Mendes de Almeida
    Pages 213-228

  13. Neurotoxicology and Disease Modelling

    • Carolina Nunes, Marie-Gabrielle Zurich
    Pages 229-246

  14. Mesenchymal Stem Cells for Cutaneous Wound Healing

    • Sérgio P. Camões, Jorge M. Santos, Félix Carvalho, Joana P. Miranda
    Pages 247-267

  15. Correction to: Cellular Reprogramming and Aging

    • Gabriela Rodrigues, Bernard A. J. Roelen
    Pages C1-C1
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Keywords

About this book

This textbook will support graduate students with learning materials rich in the basic concepts of stem cell biology, in its most widespread and updated perspective. The chapters are conceived in a way for students to understand the meaning of pluripotency, the definition of embryonic stem cells and the formation of multicellular structures such as organoids together with the underlying principles of their epigenetic. This textbook also discusses adult stem cells and the potential use of these cells, in particular neural, mesenchymal,  and several types of muscular cells, in biomedical research and clinical applications.


This textbook represents a vital complement to the text on Essential Current Concepts of Stem Cell Biology, also published in the Learning Materials in Biosciences textbook series.

Editors and Affiliations

  • Centro de Ecologia, Evolução e Alterações Ambientais, Departamento de Biologia Animal, Faculdade de Ciências da, Universidade de Lisboa, Lisbon, Portugal

    Gabriela Rodrigues

  • Embryology, Anatomy and Physiology, Department Clinical Sciences, Faculty of Veterinary Medicine, Utrecht Universtity, Utrecht, The Netherlands

    Bernard A. J. Roelen

About the editors

Gabriela Rodrigues is an Assistant Professor at the University of Lisbon where she is responsible for the course on Stem Cell Biology. 

Bernard Roelen is an Associate Professor at the Department of Farm Animal Health, Faculty of Veterinary Medicine in Utrecht University whose research focus is on mammalian germ cells and early embryonic stem cells. 


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