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Tumor Microenvironment

Molecular Players – Part A

  • Book
  • © 2020

Overview

Editors:
  1. Alexander Birbrair

    1. Department of Radiology, Columbia University Medical Center, New York, USA

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  • Provides a comprehensive overview of the state-of-the-art research on various molecular players in the tumor microenvironment, including iron, lactic acid, galectins, and oxygen
  • Illustrates in detail how cancer cells are affected by different molecules, such as Fatty acid mediators and extracellular vesicles
  • Describes how molecular components of the tumor microenvironment and cancer progression are intimately linked

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1259)

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Table of contents (9 chapters)

  1. Front Matter

    Pages i-xii
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  2. Cathepsin D in the Tumor Microenvironment of Breast and Ovarian Cancers

    • Zahidul I. Pranjol, Jacqueline L. Whatmore
    Pages 1-16

  3. Galectins in the Tumor Microenvironment: Focus on Galectin-1

    • Neus Martínez-Bosch, Pilar Navarro
    Pages 17-38

  4. Iron in the Tumor Microenvironment

    • Driton Vela
    Pages 39-51

  5. Oxygen in the Tumor Microenvironment: Mathematical and Numerical Modeling

    • Edoardo Milotti, Thierry Fredrich, Roberto Chignola, Heiko Rieger
    Pages 53-76

  6. Roles for Phospholipase D1 in the Tumor Microenvironment

    • Daniela Barisano, Michael A. Frohman
    Pages 77-87

  7. Leptin in Tumor Microenvironment

    • Adriano Angelucci, Letizia Clementi, Edoardo Alesse
    Pages 89-112

  8. The Immune Consequences of Lactate in the Tumor Microenvironment

    • Cathal Harmon, Cliona O’Farrelly, Mark W. Robinson
    Pages 113-124

  9. Fatty Acid Mediators in the Tumor Microenvironment

    • Saraswoti Khadge, John Graham Sharp, Geoffrey M. Thiele, Timothy R. McGuire, James E. Talmadge
    Pages 125-153

  10. Extracellular Vesicles in the Tumor Microenvironment: Various Implications in Tumor Progression

    • Alex C. Boomgarden, Colin Sheehan, Crislyn D’Souza-Schorey
    Pages 155-170

  11. Back Matter

    Pages 171-175
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Keywords

About this book

This book provides a comprehensive overview of the latest research on the molecular players in the tumor microenvironment, including Cathepsin D, galectins, iron, oxygen, Phospholipase D1, leptin, extracellular vesicles, and more. 

Taken alongside its companion volumes, these books update us on what we know about the tumor microenvironment as well as future directions. Tumor Microenvironment: Molecular Players – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.

Editors and Affiliations

  • Department of Radiology, Columbia University Medical Center, New York, USA

    Alexander Birbrair

About the editor

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).

Bibliographic Information

  • Book Title: Tumor Microenvironment

  • Book Subtitle: Molecular Players – Part A

  • Editors: Alexander Birbrair

  • Series Title: Advances in Experimental Medicine and Biology

  • DOI: https://doi.org/10.1007/978-3-030-43093-1

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-43092-4Published: 24 June 2020

  • Softcover ISBN: 978-3-030-43095-5Published: 24 June 2021

  • eBook ISBN: 978-3-030-43093-1Published: 23 June 2020

  • Series ISSN: 0065-2598

  • Series E-ISSN: 2214-8019

  • Edition Number: 1

  • Number of Pages: XII, 175

  • Number of Illustrations: 11 b/w illustrations, 20 illustrations in colour

  • Topics: Cell Biology, Cancer Research, Oncology

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