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Genetics of Male Infertility

A Case-Based Guide for Clinicians

Editors: Arafa, M., Elbardisi, H., Majzoub, A., Agarwal, A. (Eds.)

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  • A comprehensive and case-based overview of the genetic basis of male infertility, discussing molecular bases and consequences of genetic abnormalities
  • Presents current clinical tools for diagnosis and management of male genetic abnormalities affecting fertility, including algorithms for patient counseling
  • An essential guide for reproductive medicine specialists, andrologists, urologists and all clinicians treating infertile patients
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-37972-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-030-37971-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
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About this book

This unique, case-based guide provides a thoughtful and comprehensive overview of the genetic basis of male infertility for the practicing clinician. In addition to discussing the molecular foundations of sperm production and the consequences of genetic abnormalities on various stages of sperm development, it examines the clinical aspects of acknowledged genetic disorders and their implications on male fertility. In so doing, it offers the necessary tools required by the clinician for the diagnosis and treatment of infertile men with genetic abnormalities. Moreover, it provides essential algorithms that may aid in counseling patients in the clinic.
The text is arranged in four thematic sections for easy reference. The genetic foundation of male reproduction is presented in part 1, including regulation of sperm production, the structure of sperm chromatin, and spermatogenesis. The impact of genetic abnormalities on male infertility is the subject of part 2, covering sperm defects, mitochondrial function and DNA fragmentation. The clinical case material in part 3 illustrates real-world examples of genetic etiologies and the current diagnostic and therapeutic strategies for conditions such as vas asplasia, cryptorchidism, immotile cilia syndrome, sperm aneuploidy and other challenging scenarios. Casting forward, the fourth and final section presents an overview of future possibilities for management of genetic causes of male infertility, including gene editing.
Fully exploring the clinical context of these genetic conditions in a practical manner that appeals to the practicing clinician, Genetics of Male Infertility is an exciting and essential text for reproductive medicine specialists, andrologists, urologists, researchers and all other clinicians treating infertile patients. 

About the authors

Mohamed Arafa, MD, Department of Andrology, Cairo University, Cairo, Egypt; Department of Urology, Hamad Medical Corporation, Doha, Qatar; Department of Urology, Weill Cornell Medicine – Qatar, Doha, Qatar Haitham Elbardisi, MD, Department of Urology, Hamad Medical Corporation, Doha, Qatar; Department of Urology, Weill Cornell Medicine – Qatar, Doha, Qatar Ahmad Majzoub, MD, Department of Urology, Hamad Medical Corporation, Doha, Qatar; Department of Urology, Weill Cornell Medicine – Qatar, Doha, Qatar
Ashok Agarwal, PhD, HCLD, American Center for Reproductive Medicine, Department of Urology, Cleveland Clinic, Cleveland, OH, USA

Table of contents (22 chapters)

Table of contents (22 chapters)

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-37972-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-030-37971-1
  • Free shipping for individuals worldwide
  • Immediate ebook access, if available*, with your print order
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Genetics of Male Infertility
Book Subtitle
A Case-Based Guide for Clinicians
Editors
  • Mohamed Arafa
  • Haitham Elbardisi
  • Ahmad Majzoub
  • Ashok Agarwal
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-37972-8
DOI
10.1007/978-3-030-37972-8
Hardcover ISBN
978-3-030-37971-1
Edition Number
1
Number of Pages
XVII, 375
Number of Illustrations
3 b/w illustrations, 51 illustrations in colour
Topics

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