Nanomedicine and Nanotoxicology

Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses

Antioxidant Therapeutic Defenses

Authors: Madkour, Loutfy H.

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  • Helps understanding the molecular mechanisms underlying interconnecting pathways associated with numerous diseasesDiscusses antioxidants, therapeutic options and regulation of the immune responses 
  • Explains antioxidant therapeutic defenses towards redox biology and oxidative stress 
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eBook $169.00
price for USA in USD (gross)
  • ISBN 978-3-030-37297-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-030-37296-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides insights and tools for better understanding redox biology and medicine and, in the long run, to finding new therapeutic strategies to target dysregulated redox processes in various diseases. It presents the recent advances in new nanomedication technologies of the effects of nanoparticles NPs on oxidative stress, RONS and ER stress. The book comprises 13 chapters covering ecotoxicology, cytotoxicity, nanotoxicity and genotoxicity mechanisms causing by the role and interactions of nanoparticles and free radicals with (RONS) and (ER) stress. Endoplasmic Reticulum (ER) Stress as a mechanism for NPs induced toxicity has been discussed. The advances of nanotechnology and the effects of nanoparticles on oxidative stress, ROS and ER stress parameters are discussed. Antioxidants, therapeutic options and regulation of the immune responses are explained throughout the book.

About the authors

Prof. LOUTFY H. MADKOUR: (Egyptian) has been a Professor of Physical Chemistry, Nano Science and Nanotechnology at Chemistry Department, Faculty of Science and Arts, Al Baha University, Baljarashi, 65635, Saudi Arabia (KSA), since 2012 till now.

He received his B.Sc., M.Sc. and Ph.D. from the Cairo, Minia and Tanta Universities of the AR Egypt, respectively in Physical Chemistry. He worked as a lecturer chemistry at the Tanta University since 1982 and as a professor of physical chemistry in 1999. He has conducted a series of studies in the field of physical chemistry in the field of electrochemistry, corrosion science, density functional theory, molecular dynamic simulation, quantum, theoretical chemistry, chemical equalization principles, nanoscience, nanotechnology, Nano medicine; electrometallurgy, electroanalytical chemistry, analytical chemistry, polarography, electrolytic extraction of heavy metals from natural ores and deposits, electrochemical thermodynamics and environmental chemistry. His earlier research accomplishments include Biosynthesis of Metallic Nanoparticles (MNPs)s and toxicology studies for Pharmacological applications in medicine and therapy. He has published 150 peer-reviewed original research articles, 11 review articles, and 6 books in the area of physical chemistry, practical and applied chemistry, corrosion science, Nanoscience and Nano medicine. He is serving in different positions in Egypt, Kuwait, Yemen, and Saudi Arabia.

Prof. MADKOUR is appointed as the prestigious Editorial Board member of several international journals such as: International Journal of Industrial Chemistry (IJIC) Published by the SPRINGER;  International Journal of Ground Sediment & Water; E-Cronicon Chemistry (EC Chemistry); BAOJ Chemistry; Global Drugs and Therapeutics (GDT); Chronicles of Pharmaceutical Science (ISSN 2572-7761) journal; Journal of Targeted Drug Delivery. UNIQUE PUB INTERNATIONAL UPI Journal of Pharmaceutical, Medical and Health Sciences; and Global Journal of Nanomedicine (GJN) ISSN: 2573-2374; Research and Reviews in Computational Chemistry Journal and Journal of Pharmaceutical sciences-current research (JPSCR) in the area of Pharmaceutical, Pharmacology, Journal of Pharmacology & Pharmaceutical Research (JPPR); Archives of Pharmacy & Pharmacology Research journal- APPR and  Drug Designing & Development (NAPDD) website; the Pharmaceutical Sciences & Analytical Research Journal (PSARJ); Nanotechnology & Applications (NTA); the Clinical Pharmacology and Toxicology Research; The Laboratory Medicine Journal; Journal Drug Design Development & Therapy MEDCRAVEONLINE.COM MOJDDT; Journal of Pharmacy and Drug Development. E Scientific Publishers and ADVANCES AND APPLICATIONS OF PHARMACY Journal published online by MDPI quarterly. He has joined as an Editorial Board member in Journal of Clinical and Medical Research; International Journal of Environmental Chemistry, Science PG Publishing Group and LOJ Pharmacology & Clinical Research (LOJPCR).  He has been uploaded as the Editorial Board member in CPQ MEDICINE (CPQME) Journal and Japan Journal of Research. He has been uploaded as the Editorial Board member in Organic & Medicinal Chemistry International Journal (OMCIJ).

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Ecotoxicology of Environmental Heavy Metal Ions and Free Radicals on Macromolecule Cell Organisms

    Pages 1-46

    Madkour, Loutfy H.

  • Nanotoxicity, Cytotoxicity, and Genotoxicity Mechanisms of Nanomaterials

    Pages 47-98

    Madkour, Loutfy H.

  • Sources of Oxidants and Function of ROS Inside the Macromolecule Cells

    Pages 99-138

    Madkour, Loutfy H.

  • The Roles and Mechanisms of ROS, Oxidative Stress, and Oxidative Damage

    Pages 139-191

    Madkour, Loutfy H.

  • Consequences of Oxidative Stress and ROS-Mediated Pathways Cellular Signaling Stress Response

    Pages 193-260

    Madkour, Loutfy H.

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-3-030-37297-2
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-3-030-37296-5
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Nanoparticles Induce Oxidative and Endoplasmic Reticulum Stresses
Book Subtitle
Antioxidant Therapeutic Defenses
Authors
Series Title
Nanomedicine and Nanotoxicology
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-37297-2
DOI
10.1007/978-3-030-37297-2
Hardcover ISBN
978-3-030-37296-5
Series ISSN
2194-0452
Edition Number
1
Number of Pages
LVI, 696
Topics