Overview
- Provides a comprehensive overview of the state-of-the-art research on how the tumor microenvironment exploits signaling pathways to fuel cancer progression
- Describes several different signaling pathways in the tumor microenvironment, including S1P, neuregulin, Notch, erythropoietin, Rho-ROCK, mTOR signaling, and more.
- Illustrates in copious detail how cells in the tumor microenvironment co-opt signaling pathways to allow them to proliferate, survive, and invade other tissues.
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1223)
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Table of contents (8 chapters)
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Front Matter
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Back Matter
Keywords
- Estrogen signaling tumor microenvironment
- estrogen tumor
- RANK signaling tumor microenvironment
- Neuropilins signaling tumor microenvironment
- Eph/ephrin signaling tumor
- Rho-ROCK signaling tumor
- mTOR Signaling Tumor Microenvironment
- Renin-angiotensin system tumor
- Nitric oxide signaling tumor
- Interferon signaling tumor microenvironment
- Frizzled4 signaling tumor microenvironment
- nitric oxide signaling tumor
- toll receptor signaling tumor
About this book
Revealing essential roles of the tumor microenvironment in cancer progression, this book provides a comprehensive overview of the latest research on how different signaling pathways are important in the tumor microenvironment. Multiple signaling pathways are covered, including S1P, neuregulin, Notch, erythropoietin, Rho-ROCK, mTOR, and more.
Taken alongside its companion volumes, these books update us on what we know about various aspects of the tumor microenvironment as well as future directions. Tumor Microenvironment: Signaling Pathways – Part A is essential reading for advanced cell biology and cancer biology students as well as researchers seeking an update on research in the tumor microenvironment.
Reviews
Editors and Affiliations
About the editor
Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. His research is funded by the Serrapilheira Institute, CNPq, CAPES, and FAPEMIG. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC), and, in 2019, he was elected member of the Global Young Academy (GYA).
Bibliographic Information
Book Title: Tumor Microenvironment
Book Subtitle: Signaling Pathways – Part A
Editors: Alexander Birbrair
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-35582-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-35581-4Published: 07 February 2020
Softcover ISBN: 978-3-030-35584-5Published: 07 February 2021
eBook ISBN: 978-3-030-35582-1Published: 06 February 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: XI, 170
Number of Illustrations: 3 b/w illustrations, 35 illustrations in colour
Topics: Cell Biology, Cancer Research, Oncology