Overview
- An integrative view of tumor microenvironment and cancer metabolic adaptations, focusing different cancer contexts and interspecific cellular actions
- A wide range of traits, showing the way cancer adapts metabolically to the microenvironment
- A clear presentation of different cancer models and analytical techniques, their usefulness, advantages and limitations
Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1219)
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Table of contents (24 chapters)
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Front Matter
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Adaptive Metabolic Features Are Sustained by Tumor Microenvironment
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Front Matter
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Microenvironment and Metabolic Signalling: The Way Cancer Cells Know How to Survive
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Front Matter
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Metabolic Fitness and Therapy Response in Cancer
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Front Matter
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Keywords
About this book
In this book, we intend to present the different components of the microenvironment driving the metabolic fitness of cancer cells. Themetabolic changes required for establishing a tumor in a given microenvironment and how these metabolic changes limit the response to drugs will generally be the major items addressed. It is important to mention not only aspects of the microenvironment that stimulate metabolic changes and that select better adapted tumor cells, but also how this regulation of cell plasticity is made. Thus, the signaling pathways that orchestrate and are orchestrated throughout this panoply of metabolic rearrangements will also be addressed in this book.
The subjects will be presented from the conceptual point of view of the cross-cancer mechanisms and also particularizing some models that can be examples and enlightening within the different areas.Editors and Affiliations
About the editor
Bibliographic Information
Book Title: Tumor Microenvironment
Book Subtitle: The Main Driver of Metabolic Adaptation
Editors: Jacinta Serpa
Series Title: Advances in Experimental Medicine and Biology
DOI: https://doi.org/10.1007/978-3-030-34025-4
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: The Editor(s) (if applicable) and The Author(s), under exclusive license to Springer Nature Switzerland AG 2020
Hardcover ISBN: 978-3-030-34024-7Published: 05 March 2020
Softcover ISBN: 978-3-030-34027-8Published: 05 March 2021
eBook ISBN: 978-3-030-34025-4Published: 04 March 2020
Series ISSN: 0065-2598
Series E-ISSN: 2214-8019
Edition Number: 1
Number of Pages: VII, 443
Number of Illustrations: 1 b/w illustrations
Topics: Cancer Research, Molecular Medicine, Human Genetics, Immunology, Human Physiology, Cell Biology