HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design

A Review of 20 Years of Research

Authors: van Regenmortel, Marc

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  • Provides a broad overview to the attempts to design a preventive HIV vaccine
  • Broadens the understanding of reasons for the failure to develop a preventive HIV vaccine
  • Includes numerous critical comments from an actual point of view
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eBook $84.99
price for USA in USD (gross)
  • ISBN 978-3-030-32459-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.99
price for USA in USD
  • ISBN 978-3-030-32458-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book gathers a series of pivotal papers on the development of an HIV/AIDS vaccine published in the last two decades. Accompanied by extensive comments putting the material into an up-to-date context, all three parts of the book offer a broad overview of the numerous unsuccessful attempts made in recent years to develop a preventive HIV vaccine. Providing a detailed review and analysis of studies published from 1998 to the present day, it examines the likely reasons for the failure to develop an HIV vaccine despite multi-million dollar investments.


About the authors

Marc Van Regenmortel was a Professor of Virology at various Universities in South Africa (Stellenbosch and Cape Town) and France (Strasbourg), and was head of the Immunochemistry Laboratory at the CNRS Molecular Biology Institute in Strasbourg for 22 years. He served as President of the International Committee on Taxonomy of Viruses and published a dozen books and 420 papers and reviews on the immunochemistry of peptides and viruses, viral taxonomy and biosensor technology. He was an advisor to the South African AIDS Vaccine Initiative and is currently an associate editor of Journal of Molecular Recognition, Archives of Virology, Advances in Virus Research, Journal of Immunological Methods, Analytical Biochemistry and Frontiers in Immunology.  

He is an Adjunct Professor of the Medical University of Vienna.

Table of contents (24 chapters)

Table of contents (24 chapters)
  • What Is a B Cell Epitope

    Pages 3-15

    Van Regenmortel, Marc H V

  • Molecular Design Versus Empirical Discovery in Peptide-Based Vaccines: Coming to Terms with Fuzzy Recognition Sites and Ill-Defined Structure-Function Relationships in Immunology

    Pages 17-24

    Van Regenmortel, Marc H V

  • Synthetic Peptide Vaccines and the Search for Neutralization B Cell Epitopes

    Pages 25-37

    Van Regenmortel, Marc H V

  • Specificity, Polyspecificity and Heterospecificity of Antibody-Antigen Recognition

    Pages 39-56

    Van Regenmortel, Marc H V

  • Reductionism and the Search for Structure: Function Relationships in Antibody Molecules

    Pages 59-70

    Van Regenmortel, Marc H V

Buy this book

eBook $84.99
price for USA in USD (gross)
  • ISBN 978-3-030-32459-9
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $109.99
price for USA in USD
  • ISBN 978-3-030-32458-2
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
HIV/AIDS: Immunochemistry, Reductionism and Vaccine Design
Book Subtitle
A Review of 20 Years of Research
Authors
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-32459-9
DOI
10.1007/978-3-030-32459-9
Hardcover ISBN
978-3-030-32458-2
Edition Number
1
Number of Pages
XXVII, 364
Number of Illustrations
8 b/w illustrations, 12 illustrations in colour
Topics