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Cancer Immunology

A Translational Medicine Context

  • Describes in detail interactions between cancerous cells and various components of the innate and adaptive immune system

  • Focuses on clinical aspects in order to educate clinicians in the clinical implications of recent research and new developments

  • Updated and revised edition reflecting the latest advances in the field

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Table of contents (33 chapters)

  1. Front Matter

    Pages i-xvi
  2. Introduction on Cancer Immunology and Immunotherapy

    • Nima Rezaei, Seyed Hossein Aalaei-Andabili, Neda Amini, Farnaz Delavari, Mahsa Keshavarz-Fathi, Howard L. Kaufman
    Pages 1-9
  3. Role of Innate Immunity in Cancers and Antitumor Response

    • Masahisa Jinushi, Muhammad Baghdadi
    Pages 11-28
  4. Tumor-Associated Myeloid Cells in Cancer Progression

    • Tamara Gulic, Rita Silva-Gomes, Sadaf Davoudian, Marina Sironi, Paola Allavena, Alberto Mantovani et al.
    Pages 29-46
  5. B-Cells in Cancer Immunology: For or Against Cancer Growth?

    • Qiao Li, Qin Pan, Huimin Tao, Xiao-Lian Zhang, Shiang Huang, Alfred E. Chang
    Pages 47-62
  6. The Roles of CD4+ T-Cells in Tumor Immunity

    • Soheil Tavakolpour, Mohammad Darvishi
    Pages 63-90
  7. T-Cell Metabolism and Its Dysfunction Induced by Cancer

    • Heriberto Prado-Garcia, Rosa Sandoval-Martinez, Susana Romero-Garcia
    Pages 107-116
  8. The Role of Exhaustion in Tumor-Induced T-Cell Dysfunction in Cancer

    • Heriberto Prado-Garcia, Susana Romero-Garcia
    Pages 117-132
  9. The Role of NK Cells in Cancer

    • Vladimir Jurišić, Ana Vuletić, Katarina MirjaÄŤić Martinović, Gordana Konjević
    Pages 133-146
  10. Role of Plasmacytoid Dendritic Cells in Cancer

    • Michela Terlizzi, Chiara Colarusso, Aldo Pinto, Rosalinda Sorrentino
    Pages 147-169
  11. The CD95/CD95L Signaling Pathway: A Role in Carcinogenesis

    • AmĂ©lie FouquĂ©, Patrick Legembre
    Pages 171-188
  12. MHC Class I Molecules and Cancer Progression: Lessons Learned from Preclinical Mouse Models

    • Irene Romero, Ignacio Algarra, Angel M. Garcia-Lora
    Pages 189-204
  13. Role of Cytokines in Tumor Immunity and Immune Tolerance to Cancer

    • Lucien P. Garo, Murugaiyan Gopal
    Pages 205-233
  14. Role of Chemokines and Chemokine Receptors in Cancer

    • Pierre-Louis Loyher, Mathieu Paul Rodero, Christophe Combadière, Alexandre Boissonnas
    Pages 235-262
  15. Role of the Inflammasome in Cancer

    • Michela Terlizzi, Chiara Colarusso, Aldo Pinto, Rosalinda Sorrentino
    Pages 263-289
  16. Apoptosis and Cancer

    • Mei Lan Tan, Shahrul Bariyah Sahul Hamid, Muhammad Asyraf Abduraman, Heng Kean Tan
    Pages 307-353
  17. Endoplasmic Reticulum Stress and Autophagy in Cancer

    • Mei Lan Tan, Heng Kean Tan, Tengku Sifzizul Tengku Muhammad
    Pages 355-402
  18. Prognostic Value of Innate and Adaptive Immunity in Cancers

    • Fabio Grizzi, Elena Monica Borroni, Daniel Yiu, Floriana Maria Farina, Ferdinando Carlo Maria Cananzi, Luigi Laghi
    Pages 403-415

About this book

This book focusing on the immunopathology of cancers is published as part of the three-volume Springer series Cancer Immunology, which aims to provide an up-to-date, clinically relevant review of cancer immunology and immunotherapy. Readers will find detailed descriptions of the interactions between cancerous cells and various components of the innate and adaptive immune system. The principal focus, however, is very much on clinical aspects, the aim being to educate clinicians in the clinical implications of the latest research and novel developments in the field.

In the new edition of this very well received book, first published in 2015, the original chapters have been significantly updated and additional chapters included on, for example, current knowledge on the roles of T-helper cells and NK cells in tumor immunity, the part played by oncoviruses in the development of various cancers, and the applications of fluorescent in situ hybridization, bioluminescence, and cancer molecular and functional imaging. Cancer Immunology: A Translational Medicine Context will be of special value to clinical immunologists, hematologists, and oncologists.

Editors and Affiliations

  • Research Center for Immunodeficiencies, Children’s Medical Center, Pediatrics Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran

    Nima Rezaei

About the editor

Nima Rezaei gained his medical degree from Tehran University of Medical Sciences in 2002 and subsequently obtained an MSc in Molecular and Genetic Medicine and a PhD in Clinical Immunology and Human Genetics from the University of Sheffield, UK. He also undertook a short-term fellowship of Clinical Immunology and Bone Marrow Transplantation in the Newcastle General Hospital. Since 2010, Dr. Rezaei has worked at the Department of Immunology, School of Medicine, Tehran University of Medical Sciences. He is now the Vice Dean of International Affairs, School of Medicine, Tehran University of Medical Sciences; and co-founder and Deputy President of the Research Center for Immunodeficiencies. He is also the Founding President of Universal Scientific Education and Research Network (USERN). Dr. Rezaei has already been the director of more than 100 research projects and has designed and participated in several international collaborative projects. He is an editorial assistant or board member for more than 40 international journals. He has edited more than 10 books, has presented more than 500 lectures/posters in congresses/meetings, and has published more than 700 articles in international scientific journals.

Bibliographic Information

  • Book Title: Cancer Immunology

  • Book Subtitle: A Translational Medicine Context

  • Editors: Nima Rezaei

  • DOI: https://doi.org/10.1007/978-3-030-30845-2

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-30844-5Published: 30 January 2020

  • Softcover ISBN: 978-3-030-30847-6Published: 26 August 2021

  • eBook ISBN: 978-3-030-30845-2Published: 03 January 2020

  • Edition Number: 2

  • Number of Pages: XVI, 802

  • Number of Illustrations: 7 b/w illustrations, 143 illustrations in colour

  • Topics: Oncology, Immunology, Hematology

Buy it now

Buying options

eBook USD 119.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 159.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 219.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access