Happy Holidays—Our $30 Gift Card just for you, and books ship free! Shop now>>

Learning Materials in Biosciences

Metabolic Pathway Design

A Practical Guide

Authors: Carbonell, Pablo

Free Preview
  • Offers real-world, hands-on examples of scientific coding
  • Written for biologists and engineers alike
  • Focuses on the Design-Build-Test-Learn cycle applied to metabolic engineering
  • Includes lab protocols to explain the integration of modelling approaches
  • Provides insights into automating full processes
  • Introduces machine learning as part of pathway design
see more benefits

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-3-030-29865-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-3-030-29864-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this Textbook

This textbook presents solid tools for in silico engineering biology, offering students a step-by-step guide to mastering the smart design of metabolic pathways. The first part explains the Design-Build-Test-Learn-cycle engineering approach to biology, discussing the basic tools to model biological and chemistry-based systems. Using these basic tools, the second part focuses on various computational protocols for metabolic pathway design, from enzyme selection to pathway discovery and enumeration. In the context of industrial biotechnology, the final part helps readers understand the challenges of scaling up and optimisation. By working with the free programming language Scientific Python, this book provides easily accessible tools for studying and learning the principles of modern in silico metabolic pathway design. Intended for advanced undergraduates and master’s students in biotechnology, biomedical engineering, bioinformatics and systems biology students, the introductory sections make it also useful for beginners wanting to learn the basics of scientific coding and find real-world, hands-on examples.


About the authors

Pablo Carbonell is a senior staff scientist at the SynBioChem Centre, Manchester Institute of Biotechnology. His field of research is automated design for metabolic engineering and synthetic biology. Pablo has developed several bioretrosynthesis-based pathway design tools, including RetroPath, XTMS, EcoliTox, Selenzyme for enzyme selection and Promis for protein design. He is interested in applying the principles of machine learning and control engineering to sustainable biological design. He has contributed to the development of several theoretical models for bio-based, bionics systems – from biosensors to robotic exoskeletons.

Table of contents (9 chapters)

Table of contents (9 chapters)

Buy this book

eBook $59.99
price for USA in USD (gross)
  • ISBN 978-3-030-29865-4
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Softcover $79.99
price for USA in USD
  • ISBN 978-3-030-29864-7
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Metabolic Pathway Design
Book Subtitle
A Practical Guide
Authors
Series Title
Learning Materials in Biosciences
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-29865-4
DOI
10.1007/978-3-030-29865-4
Softcover ISBN
978-3-030-29864-7
Series ISSN
2509-6125
Edition Number
1
Number of Pages
X, 168
Number of Illustrations
44 illustrations in colour
Topics