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Molecular Genetics of Inflammatory Bowel Disease

Editors: D'Amato, Mauro, Hedin, Charlotte, Rioux, John D (Eds.)

  • Provides a complete review of existing knowledge of molecular genetics in inflammatory bowel diseases
  • Highlights the latest discoveries from molecular and genome-wide association studies
  • Gives insight into disease pathogenesis and potential targets for pharmaceutical intervention
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Buy this book

eBook $129.00
price for USA in USD (gross)
  • The eBook version of this title will be available soon
  • Due: January 30, 2020
  • ISBN 978-3-030-28703-0
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover $249.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: January 2, 2020
  • ISBN 978-3-030-28702-3
  • Free shipping for individuals worldwide
About this book

This book reaches out to a wide variety of professionals in the biomedical field with an interest in inflammatory bowel disease (IBD). Enormous progress has been made in the last few years since the publication of the first edition in the study of complex diseases and IBD, with hundreds of genomic regions identified that are associated with increased risk. Authored by leading clinical and research scientists in the field, the book includes state-of-the art synopses of recent genetic findings, and their interpretation for current and future exploitation in translational approaches to personalized medicine in IBD. The book also covers risk prediction, improved diagnostic and therapeutic precision, dissection of disease phenotypes and subtypes, identification of biomarkers, and host gene-microbiota interactions of clinical relevance.

About the authors

Charlotte Hedin, MD PhD 

Dr Charlotte Hedin is a specialist in luminal gastroenterology at the Karolinska University Hospital in Stockholm. She completed her PhD on Crohn’s disease pathogenesis at King’s College London and Queen Mary University of London. In 2017 she was awarded a UEG Rising Star award for her research in IBD, and in 2018 the Karolina prize for “Exemplary patient flow and quality work” at the Karolinska Hospital. She holds a clinical post-doctorate from the Karolinska Hospital. She is a member of the Swedish Organisation for the study of IBD (SOIBD)) and is committee member for the European Crohn’s and Colitis Organisation (ECCO). In addition she collaborates in international IBD research projects, (including the GEM project). Dr Hedin’s research focusses on delineating pathogenic pathways in IBD through studying at-risk individuals (families of IBD patients) and defining the process of mucosal healing. 

John D. Rioux, PhD

Dr John D. Rioux is a Full Professor of Medicine at Université de Montréal (UdeM) and Senior Researcher at the Montreal Heart Institute (MHI) and holder of the Canada Research Chair in Genetics and Genomic Medicine. He is a founding member of multiple international consortia and currently co-leads the International IBD Genetics Consortium, is Chair of the Steering Committee of the NIDDK IBD Genetics Consortium and is the leader of the IBD Genomic Medicine (iGenoMed) Consortium. Dr. Rioux’s research focuses on three main areas: (1) genetic studies to identify risk factors for common and rare diseases; (2) functional studies to understand how these genetic risk factors protect or predispose to disease; and (3) integrative human studies to identify predictive biomarkers of important clinical outcomes. Dr. Rioux’s work has led to over 200 publications, cited over 30,000 times. 

Mauro D’Amato, PhD

Dr Mauro D’Amato is Professor of Genetics and Genomics and Head of the Gastrointestinal Genetics Unit at the School of Biological Sciences, Faculty of Science, Monash University in Melbourne, Australia. He conceived and coordinates the largest gene-mapping effort in irritable bowel syndrome, the bellygenes initiative exploiting data from >800,000 individuals, has served in the Management Committee of several consortia including the International IBD Genetics Consortium, and is member of the European Microscopic Colitis Group. His team combine genomic, computational and pre-clinical expertise to elucidate the pathogenetic mechanisms predisposing to inflammatory and functional gastrointestinal diseases. The druggable genome, nutrigenetics and host (genome) - microbiota interactions are also new research lines within the group. D’Amato’s research has resulted in more than 150 publications and over 13,000 citations.

Buy this book

eBook $129.00
price for USA in USD (gross)
  • The eBook version of this title will be available soon
  • Due: January 30, 2020
  • ISBN 978-3-030-28703-0
  • Digitally watermarked, DRM-free
  • Included format:
  • ebooks can be used on all reading devices
Hardcover $249.99
price for USA in USD
  • Customers within the U.S. and Canada please contact Customer Service at +1-800-777-4643, Latin America please contact us at +1-212-460-1500 (24 hours a day, 7 days a week).
  • Due: January 2, 2020
  • ISBN 978-3-030-28702-3
  • Free shipping for individuals worldwide
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Genetics of Inflammatory Bowel Disease
Editors
  • Mauro D'Amato
  • Charlotte Hedin
  • John D Rioux
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-28703-0
DOI
10.1007/978-3-030-28703-0
Hardcover ISBN
978-3-030-28702-3
Edition Number
2
Number of Pages
VIII, 712
Number of Illustrations
2 b/w illustrations, 37 illustrations in colour
Topics