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Endometrial Gene Expression

An Emerging Paradigm for Reproductive Disorders

Editors: Kwak-Kim, Joanne (Ed.)

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  • Presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders
  • Discusses gene expression in cases of repeated implant failure, immune profiling, recurrent pregnancy loss, infection, uterine fibroids, endometriosis and other reproductive and gynecological malignancies
  • Ideal for for reproductive endocrinologists, gynecologists, fetal medicine specialists, and all clinicians treating female infertility
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-28584-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-030-28583-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The endometrium goes through cyclical changes under the influence of hormones, and immune effectors in the endometrium change their populations cyclically as well. Dynamic changes in immune effectors determine endometrial cytokine and chemokine milieus and, consequently, the endometrial immune response. Endometrial immune responses have been shown to be important for trophoblast invasion and early pregnancy. Indeed, dysregulated endometrial inflammatory immune responses are associated with reproductive failures, such as recurrent pregnancy losses, repeated implantation failure, and gynecological diseases with oncogenic potential. Hence, the investigation of endometrial gene expression may predict infertility, gynecological and oncological conditions. 
This book presents the state of the art in endometrial gene expression as well as recent developmental findings relating to reproduction and reproductive disorders. It begins with a review of the genetic regulation of urogenital tract formation and molecular mechanism underlying the physiology of menstrual cycle before moving on to the current and emerging technological advances in molecular biology. Endometrial gene expressions of immune inflammatory conditions, viral infection, metabolic and nutritional conditions, and reproductive disorders are then presented in following chapters. Examples of the use and interpretation of gene expression in clinical scenarios including recurrent pregnancy losses,  infertility and multiple implantation failures are presented with currently available endometrial gene analysis.
Utilizing the latest evidence and clinical guidelines, Endometrial Gene Expression will be a cutting-edge resource for gynecologist, reproductive immunologist, reproductive endocrinologists, obstetrician, maternal fetal medicine specialist and other health care providers in the field of reproductive medicine.  

About the authors

Joanne Kwak-Kim, MD, MPH, Department of Obstetrics and Gynecology, Department of Microbiology and Immunology, Chicago Medical School, Rosalind Franklin University of Medicine and Science, Vernon Hills, IL, USA.

 

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Endometrial Development and Its Fine Structure

    Pages 1-32

    Kurita, Takeshi (et al.)

  • Molecular Biology Techniques for Endometrial Gene Expression: Recent Technological Advances

    Pages 33-50

    Ni, Ke (et al.)

  • T Cell-Related Endometrial Gene Expression in Normal and Complicated Pregnancies

    Pages 51-66

    Wu, Li (et al.)

  • Role of Immunoregulatory Cytokine IL-15 in the Endometrium

    Pages 67-74

    Dambaeva, Svetlana (et al.)

  • Endometrial Immune Profiling: An Emerging Paradigm for Reproductive Disorders

    Pages 75-89

    LéDée, Nathalie

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-28584-5
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $149.99
price for USA in USD
  • ISBN 978-3-030-28583-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Endometrial Gene Expression
Book Subtitle
An Emerging Paradigm for Reproductive Disorders
Editors
  • Joanne Kwak-Kim
Copyright
2020
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-28584-5
DOI
10.1007/978-3-030-28584-5
Hardcover ISBN
978-3-030-28583-8
Edition Number
1
Number of Pages
XIII, 220
Number of Illustrations
15 illustrations in colour
Topics