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Healthy Ageing and Longevity

Early Life Origins of Ageing and Longevity

Editors: Vaiserman, Alexander (Ed.)

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  • Gathers recent research on developmental programming and age-related disease 
  • Expert contributors describe the developmental origins of adult health and disease 
  • Benefits gerontology scholars, researchers, and clinicians, as well as the general public 
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eBook $89.00
price for USA in USD (gross)
  • ISBN 978-3-030-24958-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
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  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-030-24957-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This book provides a comprehensive overview of the field of developmental programming of ageing phenotypes. Although gerontological research has traditionally focused on later stages of the life cycle, growing evidence indicates that both the rate of ageing-associated functional declines, and the risks of later-life chronic pathological conditions, can be traced to origins early in life.

While other books in the field concentrate on the developmental origin of particular disorders, this volume offers a detailed guide to all important aspects of the role of early-life conditions in programming both chronic pathological conditions and the ageing process.

Interest in the study of ageing and longevity had its beginnings in research on the fetal origins of adult disease. This has evolved into a hypothesis on the Developmental Origins of Adult Health and Disease (DOHaD), which postulates that adverse environmental exposures during critical in-utero and early postnatal stages of development may permanently change physiological responses and cause functional impairments and disorders in adult life.

In this book, the contributing authors and leading experts from around the world, describe research on mechanisms underlying the developmental programming phenomenon, as well as interventional strategies aimed at restoring developmentally disrupted epigenetic patterns.

Early Life Origins of Ageing and Longevity benefits a wide audience of working scientists, clinicians, and advanced students, and will also interest scientifically curious general readers who wish to know more about current research in this rapidly evolving field.

About the authors

Alexander Vaiserman was born in Kyiv, Ukraine, in 1957. His research interests comprise epigenetics, epidemiology and experimental gerontology. He earned his MSc Degree in cytology and developmental biology from Kyiv State University in 1984, and his DSc degrees in normal physiology from Instiute of Gerontology (Kyiv, Ukraine) in 1991 and 2004, respectively. Since 1978, he has had a permanent position in the Instiute of Gerontology (Kyiv, Ukraine). Since 2010 to present hi is the head of the Laboratory of Epigenetics in the Instiute of Gerontology (Kyiv, Ukraine). He is the member of the Editorial Boards of the journals Biogerontology, Frontiers in Genetics of Aging, Journal of Genomic Medicine and Pharmacogenomics, and Journal of Gerontology & Geriatric Research.

Table of contents (15 chapters)

Table of contents (15 chapters)
  • Epidemiology of Early Nutrition and Adult Health: Metabolic Adaptations and Body Composition

    Pages 3-22

    Hoffman, Daniel J. (et al.)

  • General Biology of the Developmental Origins of Health

    Pages 23-34

    Lampl, Michelle

  • Early Life Programming of Aging in Genetically Long-Lived Mice

    Pages 37-55

    Bartke, Andrzej (et al.)

  • Immunological Basis of In Utero Programming of Adult Disease

    Pages 57-66

    Golden, Thea N. (et al.)

  • Early Life Developmental Programming of the GH/IGF Axis and Long-Term Health

    Pages 67-86

    Reynolds, Clare M. (et al.)

Buy this book

eBook $89.00
price for USA in USD (gross)
  • ISBN 978-3-030-24958-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-030-24957-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Early Life Origins of Ageing and Longevity
Editors
  • Alexander Vaiserman
Series Title
Healthy Ageing and Longevity
Series Volume
9
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-24958-8
DOI
10.1007/978-3-030-24958-8
Hardcover ISBN
978-3-030-24957-1
Series ISSN
2199-9007
Edition Number
1
Number of Pages
XI, 310
Number of Illustrations
10 b/w illustrations, 17 illustrations in colour
Topics