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Advances in Experimental Medicine and Biology

The Drosophila Model in Cancer

Editors: Deng, Wu-Min (Ed.)

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  • Reviews use of the powerful Drosophila model for cancer studies from gene discovery to models of disease progression, to drug screening.
  • Highlights the challenges in cancer research and how the humble fruit-fly model can help
  • Offers guidance for researchers to develop new models, concepts and therapeutic strategies against cancer
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-030-23629-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-030-23628-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

This volume provides a series of review articles that capture the advances in using the fruit fly, Drosophila melanogaster, model system to address a wide range of cancer-related topics.  Articles in this book provide case studies that shed light on the intricate cellular and molecular mechanisms underlying tumor formation and progression.

 

Readers will discover the beauty of the fly model’s genetic simplicity and the vast arsenal of powerful genetic tools enabling its efficient and adaptable use.  This model organism has provided a unique opportunity to address questions regarding cancer initiation and development that would be extremely challenging in other model systems.

 

This book provides a useful resource for a researcher who wishes to learn about and apply the Drosophila model to tackle fundamental questions in cancer biology, and to find new ways to fight against this devastating disease.

About the authors

Wu-Min Deng is a Professor at the Department of Biological Sciences in Florida State University.

Table of contents (14 chapters)

Table of contents (14 chapters)
  • Drosophila Model in Cancer: An Introduction

    Pages 1-14

    Chatterjee, Deeptiman (et al.)

  • Using Drosophila Models and Tools to Understand the Mechanisms of Novel Human Cancer Driver Gene Function

    Pages 15-35

    Villegas, Santiago Nahuel (et al.)

  • Drosophila Models of Cell Polarity and Cell Competition in Tumourigenesis

    Pages 37-64

    Fahey-Lozano, Natasha (et al.)

  • Two Sides of the Same Coin – Compensatory Proliferation in Regeneration and Cancer

    Pages 65-85

    Diwanji, Neha (et al.)

  • The Initial Stage of Tumorigenesis in Drosophila Epithelial Tissues

    Pages 87-103

    Tamori, Yoichiro

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-030-23629-8
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-030-23628-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
The Drosophila Model in Cancer
Editors
  • Wu-Min Deng
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1167
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-23629-8
DOI
10.1007/978-3-030-23629-8
Hardcover ISBN
978-3-030-23628-1
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VI, 250
Number of Illustrations
1 b/w illustrations, 55 illustrations in colour
Topics