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Advances in Experimental Medicine and Biology

Breast Cancer Metastasis and Drug Resistance

Challenges and Progress

Editors: Ahmad, Aamir (Ed.)

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  • Provides comprehensive information on breast cancer disease, the factors that make it lethal, and current research progress
  • Excellent source of reference for students/beginning researchers as well as advanced and senior researchers
  • Integrates basic and translational research with clinical implications – the understanding and developments in both these worlds
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eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-030-20301-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-030-20300-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Resistance to therapies, both targeted and systemic, and metastases to distant organs are the underlying causes of breast cancer-associated mortality. The second edition of Breast Cancer Metastasis and Drug Resistance brings together some of the leading experts to comprehensively understand breast cancer: the factors that make it lethal, and current research and clinical progress. This volume covers the following core topics: basic understanding of breast cancer (statistics, epidemiology, racial disparity and heterogeneity), metastasis and drug resistance (bone metastasis, trastuzumab resistance, tamoxifen resistance and novel therapeutic targets, including non-coding RNAs, inflammatory cytokines, cancer stem cells, ubiquitin ligases, tumor microenvironment and signaling pathways such as TRAIL, JAK-STAT and mTOR) and recent developments in the field (epigenetic regulation, microRNAs-mediated regulation, novel therapies and the clinically relevant 3D models). Experts also discuss the advances in laboratory research along with their translational and clinical implications with an overarching goal to improve the diagnosis and prognosis, particularly that of breast cancer patients with advanced disease.

About the authors

Aamir Ahmad, PhD, is Assistant Professor of Oncologic Sciences at University of South Alabama’s Mitchell Cancer Institute, Mobile, AL, USA. He received his academic degrees from AMU, Aligarh, India and completed post-doctoral training at the National Cancer Institute, National Institutes of Health, Bethesda, MD, USA. His research interests include understanding the mechanisms of cancer drug resistance and metastasis in different cancers, with emphasis on the role of microRNAs, non-coding RNAs, epigenetics, exosomes, cancer stem cells and a personalized approach. He has authored 160 scientific research / review articles, edited/co-edited 8 books and serves as Expert Reviewer for scientific proposals submitted to 8 different funding agencies in Europe, Asia and Africa. He is the Founding Editor-in-Chief of the journal “Non-coding RNA Research”, Section Editor for the journal “Scientific Reports”, and is Section Editor for the journal “PLoS ONE”. He is also the Editor-in-Chief of the Elsevier series ‘Cancer Metastasis’.

Table of contents (22 chapters)

Table of contents (22 chapters)

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-3-030-20301-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-3-030-20300-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Breast Cancer Metastasis and Drug Resistance
Book Subtitle
Challenges and Progress
Editors
  • Aamir Ahmad
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1152
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-20301-6
DOI
10.1007/978-3-030-20301-6
Hardcover ISBN
978-3-030-20300-9
Series ISSN
0065-2598
Edition Number
2
Number of Pages
XVIII, 427
Number of Illustrations
9 b/w illustrations, 51 illustrations in colour
Topics