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Regenerative Medicine and Plastic Surgery

Skin and Soft Tissue, Bone, Cartilage, Muscle, Tendon and Nerves

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  • © 2019

Overview

Editors:
  1. Dominik Duscher

    1. Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic Surgery, Technical University of Munich, Munich, Germany

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    You can also search for this editor in PubMed   Google Scholar

  2. Melvin A. Shiffman

    1. Private Practice, Tustin, USA

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    You can also search for this editor in PubMed   Google Scholar

  • Presents the latest advances in the field of Regenerative Medicine in Plastic Surgery

  • Written by leading experts

  • Offers a wealth of essential information for students, beginners and experienced surgeons alike

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Table of contents (32 chapters)

  1. Front Matter

    Pages i-xxiv
    Download chapter PDF

  2. Skin and Soft Tissue Regeneration

    1. Front Matter

      Pages 1-1
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    2. Induction of the Fetal Scarless Phenotype in Adult Wounds: Impossible?

      • Michael S. Hu, Mimi R. Borrelli, Michael T. Longaker, H. Peter Lorenz
      Pages 3-17

    3. Scar Treatment and Prevention: Know Thine Enemy

      • Elizabeth A. Brett, Dominik Duscher
      Pages 19-26

    4. Challenges and Opportunities in Drug Delivery and Wound Healing

      • Matthias M. Aitzetmüller, Hans-Günther Machens, Dominik Duscher
      Pages 27-38

    5. Harvesting, Processing, and Injection of Lipoaspirate for Soft-Tissue Reconstruction: Details Make the Difference

      • Matthias A. Sauter, Elizabeth A. Brett, Matthias M. Aitzetmüller, Dominik Duscher
      Pages 39-43

    6. Adipose Tissue Complex (ATC): Cellular and Biocellular Uses of Stem/Stromal Cells and Matrix in Cosmetic Plastic, Reconstructive Surgery and Regenerative Medicine

      • Robert W. Alexander
      Pages 45-69

    7. Preparation, Characterization, and Clinical Implications of Human Decellularized Adipose Tissue Extracellular Matrix

      • Derek A. Banyard, Christos Sarantopoulos, Jade Tassey, Mary Ziegler, Evangelia Chnari, Gregory R. D. Evans et al.
      Pages 71-89

    8. Mesenchymal Cells that Support Human Skin Regeneration

      • Joanne K. Gardner, Zalitha Pieterse, Pritinder Kaur
      Pages 91-107

    9. Stem Cells and Burn

      • Anesh Prasai, Amina El Ayadi, David N. Herndon, Celeste C. Finnerty
      Pages 109-115

    10. Skin Tissue Engineering in Severe Burns: A Review on Its Therapeutic Applications

      • Alvin Wen Choong Chua, Chairani Fitri Saphira, Si Jack Chong
      Pages 117-136

    11. Skin Substitutes for Burn Wounds

      • Daniel Popp, Christian Tapking, Ludwik K. Branski
      Pages 137-146

    12. Wnt Signaling During Cutaneous Wound Healing

      • Khosrow Siamak Houschyar, Dominik Duscher, Susanne Rein, Zeshaan N. Maan, Malcolm P. Chelliah, Jung Y. Cha et al.
      Pages 147-155

    13. Drug Delivery Advances for the Regeneration of Aged Skin

      • Daniela Castillo Pérez, Matthias M. Aitzetmüller, Philipp Neßbach, Dominik Duscher
      Pages 157-164

  3. Bone Regeneration

    1. Front Matter

      Pages 165-165
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    2. Innovative Scaffold Solution for Bone Regeneration Made of Beta-Tricalcium Phosphate Granules, Autologous Fibrin Fold, and Peripheral Blood Stem Cells

      • Ciro Gargiulo Isacco, Kieu C. D. Nguyen, Andrea Ballini, Gregorio Paduanelli, Van H. Pham, Sergey K. Aityan et al.
      Pages 167-179

    3. Ordinary and Activated Bone Substitutes

      • Ilya Y. Bozo, R. V. Deev, A. Y. Drobyshev, A. A. Isaev
      Pages 181-209

    4. Absorbable Bone Substitute Materials Based on Calcium Sulfate as Triggers for Osteoinduction and Osteoconduction

      • Dominik Pförringer, Andreas Obermeier
      Pages 211-221

    5. Perivascular Progenitor Cells for Bone Regeneration

      • Carolyn Meyers, Paul Hindle, Winters R. Hardy, Jia Jia Xu, Noah Yan, Kristen Broderick et al.
      Pages 223-229

    6. Bone Repair and Regeneration Are Regulated by the Wnt Signaling Pathway

      • Khosrow Siamak Houschyar, Dominik Duscher, Zeshaan N. Maan, Malcolm P. Chelliah, Mimi R. Borrelli, Kamran Harati et al.
      Pages 231-245
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Keywords

About this book

This book presents the latest advances in the field of regenerative medicine in plastic surgery. It is the first authoritative reference documenting all the ways that plastic surgical practice and regenerative medicine science overlap or provide a road map for the future of both specialties. The Editors have provided a valuable service by gathering in one place the leading voices in these two fields in clear and concise manner.The first part introduces readers to essential principles of skin and soft tissue regeneration, e.g. the possibility of using mesenchymal stem cells for wound healing. Since bone serves as a supportive tissue in most of the body, bone regeneration is an important aspect of regenerative medicine; accordingly, the second part discusses the novel bone implants, activated bone grafts and bone tissue engineering. The book’s third part, focusing on cartilage regeneration, includes chapters on e.g. stem cells and ear regeneration. In turn, part four addresses muscle and tendon regeneration: from tendon to bone and tendon to muscle, as well as aging in the realm of muscle regeneration. Lastly, part five highlights nerve regeneration, deepening surgeons’ knowledge to help them successfully treat injuries to the peripheral neural system. 
Written by leading experts this book is an invaluable resource for researchers, students, beginners and experienced clinicians in a range of specialties.



"With beautiful clinical images and artwork, this book will be a central companion to both practicing plastic surgeons who wish to remain abreast of oncoming technologic advances and regenerative medicine researchers who wish to understand the current state of the art of surgical reconstruction."
 - Geoffrey C. Gurtner, MD, FACS
Johnson and Johnson Distinguished Professor of Surgery
Professor (by courtesy) of Bioengineering and Materials Science
Inaugural Vice Chairman of Surgery for Innovation
Stanford University School of Medicine


Editors and Affiliations

  • Department for Plastic Surgery and Hand Surgery, Division of Experimental Plastic Surgery, Technical University of Munich, Munich, Germany

    Dominik Duscher

  • Private Practice, Tustin, USA

    Melvin A. Shiffman

About the editors

Dr. Dominik Duscher MD, PhD, is the director of the Division of Experimental Plastic Surgery at Technical University of Munich. He holds a doctorate of medicine and a research doctorate focusing on Stem Cell Biology and Regenerative Medicine. After his medical education in Vienna (Medical University of Vienna), London (University College London) and Boston (Harvard Medical School) he graduated from a postdoctoral fellowship in Stem Cell Biology and Regenerative Medicine at Stanford University. For his research he received the Stanford University biomaterial research prize, and scholarships from the American Austrian Foundation and the Austrian Science Fund, among other distinctions. Dr. Duscher holds multiple patents, published more than 100 peer reviewed publications and authored more than 100 conference presentations. Dominik Duscher is the General Secretary of the European Plastic Surgery Research Council. He further acts as the Research Coordinator of the Microsurgical Education Center of the Kepler University Hospital Linz and the Young Forum of the Austrian Society for Surgery of the Hand.



Dr. Melvin A. Shiffman, MD, JD, FCLM, received his MD from Northwestern University School of Medicine in 1957 and completed his residency in general surgery in 1964 at the Veterans Administration Hospital, Long Beach, California. Since then he has been continuously involved in oncologic surgery, reconstruction, and cosmetic surgery. In 2002, Dr. Shiffman became Chair of the Section of Surgery at Tustin Hospital and Medical Center and in 2009-10 he served as President of the American College of Legal Medicine. He is Editor Emeritus of the American Journal of Cosmetic Surgery, a member of the Scientific Committee of the American Journal of Aesthetic Medicine, and an examiner for the International Board of Cosmetic Surgery. He is also a former Editor-in-Chief of both the American Journal of Cosmetic Surgery and the International Journal of Cosmetic Surgery. Dr. Shiffman is the recipient of many honors and is a fellow of various colleges and societies. He has published 320 articles, authored or edited 50 books, and written more than 210 book chapters.



Bibliographic Information

  • Book Title: Regenerative Medicine and Plastic Surgery

  • Book Subtitle: Skin and Soft Tissue, Bone, Cartilage, Muscle, Tendon and Nerves

  • Editors: Dominik Duscher, Melvin A. Shiffman

  • DOI: https://doi.org/10.1007/978-3-030-19962-3

  • Publisher: Springer Cham

  • eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)

  • Copyright Information: Springer Nature Switzerland AG 2019

  • Hardcover ISBN: 978-3-030-19961-6Published: 13 December 2019

  • Softcover ISBN: 978-3-030-19964-7Published: 12 December 2020

  • eBook ISBN: 978-3-030-19962-3Published: 27 November 2019

  • Edition Number: 1

  • Number of Pages: XXIV, 472

  • Number of Illustrations: 11 b/w illustrations, 97 illustrations in colour

  • Topics: Regenerative Medicine/Tissue Engineering, Plastic Surgery

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