Overview
- Compares the biogenesis, structure, and function of various type of mitochondria in distinct eukaryotic lineages
- Provides new a new perspective on mitochondria origin and the evolution of eukaryotic cells
- Investigates the constraints that led to the reduction of mitochondria in parasitic protists , furthering our understanding of the evolution of parasitism
Part of the book series: Microbiology Monographs (MICROMONO, volume 9)
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Table of contents (13 chapters)
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Front Matter
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Back Matter
Keywords
About this book
The new edition focuses on the latest information on mitochondrion-derived organelles, particularly on hydrogenosomes and mitosomes. It has become more and more evident that hydrogenosomes and mitosomes are just two specific members of larger family of organelles derived to various extent from mitochondria due to adaptation to oxygen-poor environment and to the parasitic life style. Since the 1st edition, investigation of free-living protists and commensals has revealed that there is a continuous spectrum of mitochondria-derived organelles from typical aerobic mitochondria, mitochondria with stepwise loss of respiratory chain complexes and with concomitant gain of anaerobic pathways (particularly hydrogenase), via hydrogenosomes and mitosomes to the newly discovered organisms that completely lost mitochondria.
Most of the experimental data collected relates to the human pathogens Trichomonas vaginalis harboring hydrogenosomes, and Giardia intestinalis and Entamoeba histolytica with mitosoms. In principle, hydrogenosomes are hydrogen and ATP producing organelles, while the only known function in Giardia mitosomes is synthesis of iron-sulfur clusters, whereas mitosomes of E. histolytica possess the recently discovered sulfur activation pathway. Functions of other unusual mitochondria are mostly predicted based on transcriptomic/genomic analyses as corresponding organisms are not amenable to biochemical studies.
Investigations on evolution and function of mitochondria-derived organelles substantially changed conventional views on mitochondrion from textbook models of an oxygen-consuming powerhouse of cells to a large family of organelles, variables in their structure and function in which hydrogenosomes and mitosome represent the most divergent anaerobic members.Editors and Affiliations
Bibliographic Information
Book Title: Hydrogenosomes and Mitosomes: Mitochondria of Anaerobic Eukaryotes
Editors: Jan Tachezy
Series Title: Microbiology Monographs
DOI: https://doi.org/10.1007/978-3-030-17941-0
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-17940-3Published: 22 August 2019
Softcover ISBN: 978-3-030-17943-4Published: 23 August 2020
eBook ISBN: 978-3-030-17941-0Published: 10 August 2019
Series ISSN: 1862-5576
Series E-ISSN: 1862-5584
Edition Number: 2
Number of Pages: VIII, 326
Number of Illustrations: 35 b/w illustrations, 17 illustrations in colour
Topics: Eukaryotic Microbiology, Cell Biology, Evolutionary Biology, Biochemistry, general