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Stress Challenges and Immunity in Space

From Mechanisms to Monitoring and Preventive Strategies

  • Book
  • © 2020

Overview

  • Presents a comprehensive summary of Stress-Immune interaction in extreme environments of space and its analogues

  • Bridges fundamental and applied sciences and technology to understand and counteract unfavourable effects in space and on Earth (patients)

  • Provides enough “depth” for experts to look up interactions, in a style that can be read and understood by students

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Table of contents (40 chapters)

  1. Introduction

  2. Stress and Immunity Research: A Link Between Space and Earth

  3. Stress and Immune Allostasis in Space, from Brain to Immune Responses

Keywords

About this book

This book explains how stress – either psychological or physical – can activate and/or paralyse human innate or adaptive immunity. Adequate immunity is crucial for maintaining health, both on Earth and in space. During space flight, human physiology is specifically challenged by complex environmental stressors, which are most pronounced during lunar or interplanetary missions. Adopting an interdisciplinary approach, the book identifies the impact of these stressors – the space exposome – on immunity as a result of (dys-)functions of specific cells, organs and organ networks. These conditions (e.g. gravitation changes, radiation, isolation/confinement) affect immunity, but at the same time provide insights that may help to prevent, diagnose and address immune-related health alterations. Written by experts from academia, space agencies and industry, the book is a valuable resource for professionals, researchers and students in the field of medicine, biology and technology.

The chapters “The Impact of Everyday Stressors on the Immune System and Health”, “Stress and Radiation Responsiveness” and “Assessment of Radiosensitivity and Biomonitoring of Exposure to Space adiation” are available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.





 

 

 

Editors and Affiliations

  • Laboratory of Translational Research Stress and Immunity Department of Anaesthesiology, Hospital of the University of Munich (LMU), Munich, Germany

    Alexander Choukèr

About the editor

Alexander Choukèr is Professor of Medicine and Academic Director at the Ludwig Maximilians University (LMU) in Munich, Germany and guest lecturer at King´s College, London, UK. He is clinical specialist in anesthesiology at the University Hospital where heads the “Stress and Immunity” research.  He completed his medical and immunological training at the LMU and at the National Institutes of Allergy and Infectious Diseases (NIAID), Bethesda/USA, respectively. For more than two decades he has been actively involved in research on the International Space Station, in space analogue environments and been leading inter-disciplinary teams for translational and experimental research, including at the hospital. He is member of the European Space Sciences Committee (ESSC) and has been advisor or chairman at different expert boards of the European Space Agency´s (ESA). He is the chair of the ESA Topical Team on Stress and Immunology.

Bibliographic Information

  • Book Title: Stress Challenges and Immunity in Space

  • Book Subtitle: From Mechanisms to Monitoring and Preventive Strategies

  • Editors: Alexander Choukèr

  • DOI: https://doi.org/10.1007/978-3-030-16996-1

  • Publisher: Springer Cham

  • eBook Packages: Medicine, Medicine (R0)

  • Copyright Information: Springer Nature Switzerland AG 2020

  • Hardcover ISBN: 978-3-030-16995-4Published: 06 December 2019

  • Softcover ISBN: 978-3-030-16998-5Published: 03 December 2020

  • eBook ISBN: 978-3-030-16996-1Published: 27 November 2019

  • Edition Number: 2

  • Number of Pages: XVI, 771

  • Number of Illustrations: 25 b/w illustrations, 112 illustrations in colour

  • Topics: Medicine/Public Health, general, Aerospace Technology and Astronautics, Human Physiology, Immunology, Neurosciences

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