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Current Topics in Microbiology and Immunology

Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori

Editors: Backert, Steffen (Ed.)

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  • Broadens the reader’s understanding of host-pathogen interactions regarding Helicobacter pylori
  • Provides new insights into the context of gastric inflammation and carcinogenesis
  • Reviews the impact of H. pylori virulence factors on the host’s immune system
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eBook $109.00
price for USA in USD
  • ISBN 978-3-030-15138-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
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  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
Softcover $139.99
price for USA in USD
About this book

This book focuses on immune reactions and interactions of humans with Helicobacter pylori - a human pathogen connected to gastritis, peptic ulcers and even gastric cancer. With nearly half of the world’s population colonized, it has been characterized as one of the most successful pathogens for more than 100,000 years of co-evolution with its host. The respective chapters discuss not only how H. pylori infection is considered a paradigm for persistent bacterial infection and chronic inflammation, but also how the infection might be connected to host protection against gastro-esophageal diseases, asthma, and other allergic disease manifestations. Readers will gain essential insights into the roles of specific factors in the immune response and learn about the impact of genetic polymorphisms on the risk of gastric carcinogenesis. In addition, the book discusses the strategies used by this bacterium, which allow it to colonize specific sites in the stomach, interact with the microbiome, evade immune surveillance and undermine the resolution of inflammation during persistent infection.

This volume presents a concise summary of recent advances in the areas of induction, resolution and escape of inflammation, innate and adaptive immunity, gastric disease development, as well as treatment and vaccination against H. pylori. Accordingly, it offers a valuable asset for scientists and clinicians alike.

 

About the authors

Prof. Dr. rer. nat. Steffen Backert
Chair of Microbiology
Friedrich Alexander University Erlangen/Nuremberg
Department of Biology
Division of Microbiology
Staudtstr. 5
D-91058 Erlangen
Germany
Tel.  ++49 9131 8528081
Fax  ++49 9131 8528082 

Table of contents (13 chapters)

Table of contents (13 chapters)
  • Inflammation, Immunity, and Vaccine Development for the Gastric Pathogen Helicobacter pylori

    Pages 1-19

    Ikuse, Tamaki (et al.)

  • Impact of Helicobacter pylori Virulence Factors on the Host Immune Response and Gastric Pathology

    Pages 21-52

    Javed, Sundus (et al.)

  • Genetic Polymorphisms in Inflammatory and Other Regulators in Gastric Cancer: Risks and Clinical Consequences

    Pages 53-76

    Rudnicka, Karolina (et al.)

  • MALT Lymphoma as a Model of Chronic Inflammation-Induced Gastric Tumor Development

    Pages 77-106

    Marcelis, Lukas (et al.)

  • Crosstalk Between DNA Damage and Inflammation in the Multiple Steps of Gastric Carcinogenesis

    Pages 107-137

    Sokolova, Olga (et al.)

Buy this book

eBook $109.00
price for USA in USD
  • ISBN 978-3-030-15138-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
Softcover $139.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Molecular Mechanisms of Inflammation: Induction, Resolution and Escape by Helicobacter pylori
Editors
  • Steffen Backert
Series Title
Current Topics in Microbiology and Immunology
Series Volume
421
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-15138-6
DOI
10.1007/978-3-030-15138-6
Hardcover ISBN
978-3-030-15137-9
Softcover ISBN
978-3-030-15140-9
Series ISSN
0070-217X
Edition Number
1
Number of Pages
XXIV, 359
Number of Illustrations
1 b/w illustrations, 28 illustrations in colour
Topics