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  • © 2019

Stem Cells Heterogeneity in Cancer

  • International expertise and experience in one volume
  • Comprehensive; provides background and current information and applications
  • Cogent organization, disease by disease, allowing quick access to specific information

Part of the book series: Advances in Experimental Medicine and Biology (AEMB, volume 1139)

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Table of contents (12 chapters)

  1. Front Matter

    Pages i-xii
  2. Multilayered Heterogeneity of Glioblastoma Stem Cells: Biological and Clinical Significance

    • Daniel V. Brown, Stanley S. Stylli, Andrew H. Kaye, Theo Mantamadiotis
    Pages 1-21
  3. Heterogeneity of Head and Neck Squamous Cell Carcinoma Stem Cells

    • Xu Qian, Xiaobo Nie, Barbara Wollenberg, Holger Sudhoff, Andreas M. Kaufmann, Andreas E. Albers
    Pages 23-40
  4. Heterogeneity of Small Cell Lung Cancer Stem Cells

    • D. Prabavathy, Niveditha Ramadoss
    Pages 41-57
  5. Heterogeneity of Hepatic Cancer Stem Cells

    • Caecilia H. C. Sukowati
    Pages 59-81
  6. Heterogeneity and Plasticity of Breast Cancer Stem Cells

    • Bárbara Sousa, Ana Sofia Ribeiro, Joana Paredes
    Pages 83-103
  7. Heterogeneity of Melanoma with Stem Cell Properties

    • Elisabeth A. Seftor, Naira V. Margaryan, Richard E. B. Seftor, Mary J. C. Hendrix
    Pages 105-114
  8. Heterogeneity of Colon Cancer Stem Cells

    • Akihiro Hirata, Yuichiro Hatano, Masayuki Niwa, Akira Hara, Hiroyuki Tomita
    Pages 115-126
  9. Urothelial Cancer Stem Cell Heterogeneity

    • Michaela Kripnerova, Hamendra Singh Parmar, Martin Pesta, Michaela Kohoutova, Jitka Kuncova, Karel Drbal et al.
    Pages 127-151
  10. Acute Myeloid Leukemia Stem Cell Heterogeneity and Its Clinical Relevance

    • Theodoros Karantanos, Richard J. Jones
    Pages 153-169
  11. The Heterogeneity of Osteosarcoma: The Role Played by Cancer Stem Cells

    • Kristina Schiavone, Delphine Garnier, Marie-Francoise Heymann, Dominique Heymann
    Pages 187-200
  12. Ovarian Cancer Stem Cell Heterogeneity

    • Jiri Hatina, Maximilian Boesch, Sieghart Sopper, Michaela Kripnerova, Dominik Wolf, Daniel Reimer et al.
    Pages 201-221
  13. Back Matter

    Pages 223-228

About this book

This book presents a comprehensive discussion on the heterogeneity existing between different types of stem cells within the same tissue, for several types of cancers, e.g. glioblastoma stem cells. Recent developments have revealed completely different roles of distinct stem cells within the same organ.


Thus, Stem Cells Heterogeneity in Cancer provides a timely update us on the current information on stem cells heterogeneity in various tissues. It also provides a solid foundation of the history of stem cells from specific tissues and the current applications of this knowledge in regenerative medicine. When taken as a whole, alongside its companion volumes Stem Cells Heterogeneity – Novel Concepts, and Stem Cells Heterogeneity in Different Organs, these three books present a comprehensive reference on stem cell heterogeneity in various tissues and current and future applications for regenerative medicine. It is essential reading for advanced cell biology students as well as researchers in stem cells and clinicians. 

Editors and Affiliations

  • Department of Pathology, Federal University of Minas Gerais, Department of Radiology, Columbia University Medical Center, New York, NY, USA, Belo Horizonte, MG, Brazil

    Alexander Birbrair

About the editor

Alexander Birbrair received his Bachelor’s Biomedical degree from Santa Cruz State University in Brazil. He moved to North Carolina, where he finished his PhD in Neuroscience under the mentorship of Osvaldo Delbono. Then, he joined as a posdoc in Stem Cell Biology at Paul Frenette’s laboratory at Albert Einstein School of Medicine. In 2016, he was appointed faculty at Federal University of Minas Gerais in Brazil, where he started his own lab. His laboratory is interested in understanding how the cellular components of different tissues function and control disease progression. His group explores the roles of specific cell populations in the tissue microenvironment by using state-of-the-art techniques. In 2018, Alexander was elected affiliate member of the Brazilian Academy of Sciences (ABC).

Bibliographic Information

Buy it now

Buying options

eBook USD 99.00
Price excludes VAT (USA)
  • Available as EPUB and PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book USD 129.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info
Hardcover Book USD 179.99
Price excludes VAT (USA)
  • Durable hardcover edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Other ways to access