Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization

Editors: Kök, Fatma Neşe, Yildiz, Ahu Arslan, Inci, Fatih (Eds.)

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  • Provides fundamental knowledge on biomimetic lipid membranes
  • Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques
  • Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques
  • Describes the integration of biomimetic membranes with current top-notch tools and platforms
  • Examines applications in medicine, pharmaceutical industry, and environmental monitoring
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  • ISBN 978-3-030-11596-8
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  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-030-11595-1
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  • Usually dispatched within 3 to 5 business days.
About this book

This book compiles the fundamentals, applications and viable product strategies of biomimetic lipid membranes into a single, comprehensive source. It broadens its perspective to interdisciplinary realms incorporating medicine, biology, physics, chemistry, materials science, as well as engineering and pharmacy at large. The book guides readers from membrane structure and models to biophysical chemistry and functionalization of membrane surfaces. It then takes the reader through a myriad of surface-sensitive techniques before delving into cutting-edge applications that could help inspire new research directions. With more than half the world's drugs and various toxins targeting these crucial structures, the book addresses a topic of major importance in the field of medicine, particularly biosensor design, diagnostic tool development, vaccine formulation, micro/nano-array systems, and drug screening/development.

  • Provides fundamental knowledge on biomimetic lipid membranes;
  • Addresses some of biomimetic membrane types, preparation methods, properties and characterization techniques;
  • Explains state-of-art technological developments that incorporate microfluidic systems, array technologies, lab-on-a-chip-tools, biosensing, and bioprinting techniques;
  • Describes the integration of biomimetic membranes with current top-notch tools and platforms;
  • Examines applications in medicine, pharmaceutical industry, and environmental monitoring.

About the authors

Dr. Fatma Neşe KÖK is currently Associated Professor in the Molecular Biology and Genetics Department of Istanbul Technical University, Turkey. She graduated from the Chemical Engineering Department at the Middle East Technical University and received her M.Sc. and Ph.D degrees from Biotechnology Program at the same University in 1997 and 2001, respectively. After receiving a postdoctoral research fellowship from the Alexander von Humboldt Foundation, she spent 2.5 years in Germany, in a joint project of Max Planck Institute (MPI) for Polymer Research (Mainz) and MPI for Biochemistry (Martinstred) (2002-2005) working on artificial lipid membranes. Her research interests include biomaterials and tissue engineering scaffold design, biosensors, controlled release systems, and construction and characterization of artificial lipid bilayers. 

Dr. Ahu Arslan Yildiz is currently Assistant Professor in the Bioengineering Department at the Izmir Institute of Technology (IZTECH). Previously, she was an Assistant Professor at Okan University's Genetics and Bioengineering Department and a visiting fellow at the Canary Center for Cancer Early Detection, Department of Radiology, Stanford University School of Medicine. She received her BSc degree in Chemistry in 2003 from Hacettepe University and the MSc degree in 2006 in Chemistry from Middle East Technical University. She received her Ph.D. in Biology in 2010 from the Max-Planck Institute Polymer Research and Johannes Gutenberg University. She specializes in the field of artificial cell membrane and membrane receptor research. Her research interests include applications of biotechnology, including biomimetic systems, biomaterials, tissue engineering and regenerative medicine, 3D cell culture, diagnostic tools, drug screening and lab-on-a-chip microfluidic devices.

Dr. Fatih Inci is currently working as a Research Scientist (Faculty/Academic Staff) at Stanford University School of Medicine, Canary Center at Stanford for Cancer Early Detection. Dr. Inci received his PhD degree from Istanbul Technical University (Turkey), focusing on artificial lipid membranes and their clinical and pharmaceutical applications on surface-sensitive platforms. During his Ph.D. studies, he was also appointed as a visiting scientist at the University of New South Wales (Sydney, Australia) and University of Technology Sydney (Australia). He also worked as a research scholar at Brigham and Women’s Hospital (BWH)-Harvard Medical School, and Harvard-MIT Health Sciences and Technology Division (Boston, MA, United States). Dr. Inci was then appointed a Postdoctoral Research Fellow at BWH-Harvard Medical School and Stanford University School of Medicine (Palo Alto, CA, United States) in 2013 and 2014, respectively. Dr. Inci’s area of excellence in research is to create micro- and nano-scale platform technologies in the fields of biomedical engineering, biotechnology and medicine by manipulating biomolecules, cells, and viruses in micro and nano-scale entities. His platform offers precise solutions for real-world challenges in clinical diagnostics, personalized medicine, cancer early detection, forensic science, and biomarker discovery. His research interests also focus on many applications of microfluidics, biosensors, nanoplasmonics, lab-on-a-chip, artificial lipid membranes, disease on-chip models, and drug delivery systems.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Structural and Mechanical Characterization of Supported Model Membranes by AFM

    Gumí-Audenis, Berta (et al.)

    Pages 1-27

  • To Image the Orientation and Spatial Distribution of Reconstituted Na+,K+-ATPase in Model Lipid Membranes

    Bhatia, Tripta (et al.)

    Pages 29-46

  • Asymmetric Model Membranes: Frontiers and Challenges

    Nguyen, Michael H. L. (et al.)

    Pages 47-71

  • Modeling of Cell Membrane Systems

    Özal İldeniz, Tuğba Arzu

    Pages 73-108

  • Molecular Dynamics Studies of Nanoparticle Transport Through Model Lipid Membranes

    Jameson, Cynthia J. (et al.)

    Pages 109-165

Buy this book

eBook $129.00
price for USA in USD (gross)
  • ISBN 978-3-030-11596-8
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $169.99
price for USA in USD
  • ISBN 978-3-030-11595-1
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Biomimetic Lipid Membranes: Fundamentals, Applications, and Commercialization
Editors
  • Fatma Neşe Kök
  • Ahu Arslan Yildiz
  • Fatih Inci
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-11596-8
DOI
10.1007/978-3-030-11596-8
Hardcover ISBN
978-3-030-11595-1
Edition Number
1
Number of Pages
XXIX, 306
Number of Illustrations
2 b/w illustrations, 87 illustrations in colour
Topics