Advances in Experimental Medicine and Biology

Bioactive Lipids in Health and Disease

Editors: Trostchansky, Andres, Rubbo, Homero (Eds.)

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  • Lipidomic analysis of key metabolic processes
  • Novel lipid- based therapeutic proposal for neurodegenerative diseases
  • 12 chapters and almost 50 color figures and tables
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eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-030-11488-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-030-11487-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The purpose of this book is to introduce the readers on the perspective of the role that unsaturated fatty acids and complex lipids play on health and disease. Bioactive lipids can be modified affecting membrane composition, structure and fluidity in addition to changes in cell signaling associated to lipid-protein (membrane receptors) interactions, issues that are addressed by the authors. This book analyzes key topics involving bioactive lipids and their role in normal signaling and the mechanisms of disease. The book navigates from structural studies of oxidized and non-oxidized lipids to the reactions and cell signaling processes that bioactive lipids play in cardiovascular and neurodegenerative diseases. The book contains the recent advances reported in the literature about lipidomics as well as the role that lipid-derived compounds exert on unfolded protein response and lipid metabolism and disease. This book represents a state of the art introduction to lipid metabolism from a biochemical to an in vivo overview being an useful tool for students and investigators. We hope the mechanistic observations on the role of bioactive lipids in health and disease serve a perspective to improve the existing treatments or propose new lipid-based pharmacology

About the authors

Andres Trostchansky is an associate professor of Biochemistry at the University de la Republica in Montevideo, Uruguay. He has received the Roberto Caldeyro Barcia Award in Biology.
Homero Rubbo is a professor in the department of Biochemistry at the University de la Republica in Montevideo, Uruguay.

Table of contents (12 chapters)

Table of contents (12 chapters)
  • Diffusion and Transport of Reactive Species Across Cell Membranes

    Möller, Matias N. (et al.)

    Pages 3-19

  • Characterization of Hydroxy and Hydroperoxy Polyunsaturated Fatty Acids by Mass Spectrometry

    Derogis, Priscilla Bento Matos Cruz (et al.)

    Pages 21-35

  • Understanding Peroxisome Proliferator-Activated Receptors: From the Structure to the Regulatory Actions on Metabolism

    Lamas Bervejillo, María (et al.)

    Pages 39-57

  • Diminishing Inflammation by Reducing Oxidant Generation: Nitrated Fatty Acid-Mediated Inactivation of Xanthine Oxidoreductase

    Kelley, Eric E.

    Pages 59-65

  • Unfolded Protein Response: Cause or Consequence of Lipid and Lipoprotein Metabolism Disturbances?

    Pinto, Bruno Araújo Serra (et al.)

    Pages 67-82

Buy this book

eBook $139.00
price for USA in USD (gross)
  • ISBN 978-3-030-11488-6
  • Digitally watermarked, DRM-free
  • Included format: PDF, EPUB
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $179.99
price for USA in USD
  • ISBN 978-3-030-11487-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Bioactive Lipids in Health and Disease
Editors
  • Andres Trostchansky
  • Homero Rubbo
Series Title
Advances in Experimental Medicine and Biology
Series Volume
1127
Copyright
2019
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-11488-6
DOI
10.1007/978-3-030-11488-6
Hardcover ISBN
978-3-030-11487-9
Series ISSN
0065-2598
Edition Number
1
Number of Pages
VIII, 198
Number of Illustrations
6 b/w illustrations, 35 illustrations in colour
Topics