Editors:
- First Handbook of Experimental Pharmacology on sleep and wakefulness, in which the pharmacology of sleep is discussed very much in the context of current knowledge of sleep function, its neuroanatomical and neurochemical bases, and including circadian rhythmicity
- Powerful state-of-the-art methodologies are covered, such as optogenetics and designer receptor manipulations
- Sleep- and wake-promoting compounds are not discussed in isolation, but within a single volume, which helps the understanding of their interrelationships
Part of the book series: Handbook of Experimental Pharmacology (HEP, volume 253)
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Table of contents (18 chapters)
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Front Matter
About this book
This volume connects current ideas and concepts about sleep functions and circadian rhythms with the search for novel target-selective sleep-wake therapeutics. To do so, it provides a timely, state-of-the-art overview of sleep-wake mechanisms in health and disease, ongoing developments in drug discovery, and their prospects for the clinical treatment of sleep-disordered patients. It particularly focuses on the concept that sleep and wakefulness mutually affect each other, and the future therapeutic interventions with either sleep- or wake-promoting agents that are expected to not only improve the quality of sleep but also the waking behavior, cognition, mood and other sleep-associated physiological functions.
The chapter 'Sleep Physiology, Circadian Rhythms, Waking Performance and the Development of Sleep-Wake Therapeutics' available open access under a CC BY 4.0 license at link.springer.com
Editors and Affiliations
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Human Sleep Psychopharmacology Laboratory, Institute of Pharmacology and Toxicology, University of Zürich, Zürich, Switzerland
Hans-Peter Landolt
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Surrey Sleep Research Centre, Faculty of Health and Medical Sciences, University of Surrey, Guildford, UK
Derk-Jan Dijk
Bibliographic Information
Book Title: Sleep-Wake Neurobiology and Pharmacology
Editors: Hans-Peter Landolt, Derk-Jan Dijk
Series Title: Handbook of Experimental Pharmacology
DOI: https://doi.org/10.1007/978-3-030-11272-1
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2019
Hardcover ISBN: 978-3-030-11270-7Published: 19 September 2019
eBook ISBN: 978-3-030-11272-1Published: 03 September 2019
Series ISSN: 0171-2004
Series E-ISSN: 1865-0325
Edition Number: 1
Number of Pages: X, 481
Number of Illustrations: 14 b/w illustrations, 42 illustrations in colour
Topics: Pharmacology/Toxicology, Neurosciences, Behavioral Sciences, Psychiatry, Neurology