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Springer Theses

Surface Enhanced Raman Spectroscopy for Biophysical Applications

Using Plasmonic Nanoparticle Assemblies

Authors: Fasolato, Claudia

  • Nominated as an outstanding Ph.D. thesis by the Sapienza University, Rome, Italy
  • Provides an instructive introduction to Raman- and surface-enhanced Raman spectroscopy, including both theory and state of the art 
  • Features applications in different fields of biophysics, including nanomedicine
  • Presents the design of a nanosensor for cancer diagnostics and therapy at the single-cell level
  • Offers a step-by-step description of the adopted experimental and analytical protocols 
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eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-03556-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-3-030-03555-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

The book explores the phenomenon of surface-enhanced Raman scattering (SERS), the huge amplification of Raman signal from molecules in the proximity of a metallic nanostructured surface, allowing readers to gain an in-depth understanding of the mechanisms affecting the spectroscopic response of SERS-active systems for effective applications. SERS spectroscopy is an ultrasensitive analytical technique with great potential for applications in the field of biophysics and nanomedicine. As examples, the author presents the design of nanocolloid-based SERS-active substrates for molecular sensing and of a folate-based SERS-active nanosensor capable of selectively interacting with cancer cells, enabling cancer diagnostics and therapy at the single-cell level. The author also suggests novel paths for the systematization of the SERS nanosystem design and experimental protocols to maximize sensitivity and reproducibility, which is essential when real-world biomedical applications are the goal of the study. With a combined approach, both fundamental and applied, and a detailed analysis of the state of the art, this book provides a valuable overview both for students new to SERS spectroscopy and for experts in the field.

About the authors

Claudia Fasolato received her Master Degree in Condensed Matter Physics in October 2013. She started her Ph.D. in Sapienza University in November 2013 working on plasmonic nanoparticle assemblies for Surface Enhanced Raman Spectroscopy under the supervision of Prof. P. Postorino. In February 2017, she was awarded her Ph.D. in Physics summa cum laude. Since April 2017, she has worked as a postdoc in the Nanophononics Group of Prof. I. Zardo at the University of Basel.

Table of contents (6 chapters)

  • Introduction

    Fasolato, Claudia

    Pages 1-8

  • Traditional Raman and SERS: Fundamentals and State of the Art

    Fasolato, Claudia

    Pages 9-56

  • Investigation on Nanoparticles and Their Molecular Functionalization

    Fasolato, Claudia

    Pages 57-83

  • Nanoparticle-Based SERS Substrates for Molecular Sensing Applications

    Fasolato, Claudia

    Pages 85-112

  • SERS-Active Nanovectors for Single-Cell Cancer Screening and Theranostics

    Fasolato, Claudia

    Pages 113-135

Buy this book

eBook $109.00
price for USA in USD (gross)
  • ISBN 978-3-030-03556-3
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $139.99
price for USA in USD
  • ISBN 978-3-030-03555-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Surface Enhanced Raman Spectroscopy for Biophysical Applications
Book Subtitle
Using Plasmonic Nanoparticle Assemblies
Authors
Series Title
Springer Theses
Copyright
2018
Publisher
Springer International Publishing
Copyright Holder
Springer Nature Switzerland AG
eBook ISBN
978-3-030-03556-3
DOI
10.1007/978-3-030-03556-3
Hardcover ISBN
978-3-030-03555-6
Series ISSN
2190-5053
Edition Number
1
Number of Pages
XVIII, 155
Number of Illustrations
15 b/w illustrations, 59 illustrations in colour
Topics