Overview
- Offers new insights into the fascinating area of HIV latency and persistence from multiple perspectives and scientific directions
- Provides in-depth analyses of current concepts, paradigms and ideas that drive the HIV-1 cure agenda
- Identifies areas that require specific emphasis in future studies
Part of the book series: Current Topics in Microbiology and Immunology (CT MICROBIOLOGY, volume 417)
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Table of contents (9 chapters)
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Front Matter
Keywords
About this book
This volume summarizes recent advances in understanding the mechanisms of HIV-1 latency, in characterizing residual viral reservoirs, and in developing targeted interventions to reduce HIV-1 persistence during antiretroviral therapy. Specific chapters address the molecular mechanisms that govern and regulate HIV-1 transcription and latency; assays and technical approaches to quantify viral reservoirs in humans and animal models; the complex interchange between viral reservoirs and the host immune system; computational strategies to model viral reservoir dynamics; and the development of therapeutic approaches that target viral reservoir cells. With contributions from an interdisciplinary group of investigators that cover a broad spectrum of subjects, from molecular virology to proof-of-principle clinical trials, this book is a valuable resource for basic scientists, translational investigators, infectious-disease physicians, individuals living with HIV/AIDS and the general public.
Editors and Affiliations
About the editors
Guido Silvestri
Emory University School of Medicine, Atlanta, GA 30329, USA
gsilves@emory.edu
Mathias Lichterfeld
The Brigham and Women’s Hospital and the Ragon Institute of MGH, MIT and Harvard, Boston, MA, USA
MLICHTERFELD@mgh.harvard.edu
Bibliographic Information
Book Title: HIV-1 Latency
Editors: Guido Silvestri, Mathias Lichterfeld
Series Title: Current Topics in Microbiology and Immunology
DOI: https://doi.org/10.1007/978-3-030-02816-9
Publisher: Springer Cham
eBook Packages: Biomedical and Life Sciences, Biomedical and Life Sciences (R0)
Copyright Information: Springer Nature Switzerland AG 2018
Hardcover ISBN: 978-3-030-02815-2Published: 25 October 2018
Softcover ISBN: 978-3-030-13214-9Published: 10 December 2019
eBook ISBN: 978-3-030-02816-9Published: 11 October 2018
Series ISSN: 0070-217X
Series E-ISSN: 2196-9965
Edition Number: 1
Number of Pages: VII, 248
Topics: Immunology, Virology, Pathology, Epidemiology