Happy holidays from us to you—get up to $30 off your next print or eBook! Shop now >>

Methods in Molecular Biology

Gene Therapy of Cancer

Methods and Protocols

Editors: Walther, Wolfgang, Stein, Ulrike S. (Eds.)

  • Describes a broad array of different strategies and methods such as for immunogene therapy, antitumor vaccination, oncolytic virotherapy, and suicide gene therapy
  • Provides state-of-the-art protocols and overview chapters for cancer gene therapy, along with step-by-step procedures and instructions for gene therapeutic strategies, including notes and tips for troubleshooting to avoid pitfalls
  • Explores nonviral and viral vectors and relevant gene transfer/delivery systems
  • Includes methods and backgrounds of experimental and clinical gene therapy approaches
  • Covers the important issue of vector design and vector production for clinical applications
  • Features the current regulatory and ethical aspects in translating experimental approaches into clinical application of gene therapy to patients
see more benefits

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-59745-561-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-934115-85-5
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-61737-946-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Despite various difficulties, the field of gene therapy, particularly with regard to cancer, has accumulated a tremendous amount of vital pre-clinical and clinical data. Gene Therapy of Cancer: Methods and Protocols, Second Edition fully updates the first edition with expert coverage of established and novel protocols involving both experimental and clinical approaches to cancer gene therapy. This state-of-the-art volume contains overviews of new concepts and strategies with chapters on regulatory and ethical issues, developments, problems and possible limitations of design and production of gene therapeutics as well as translational issues. Written in the highly successful Methods in Molecular Biology™ series format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible protocols, and notes on troubleshooting and avoiding known pitfalls.

Cutting edge and authoritative, Gene Therapy of Cancer: Methods and Protocols, Second Edition is an ideal guide for all those who wish to explore the fast-paced and critical study of nonviral, viral, experimental and clinical cancer gene therapy.

Reviews

From the reviews of the second edition:

“This book, authored by a number of prominent researchers in the field … provides an overview of recent ground-breaking experimental and clinical concepts and protocols in cancer gene therapy. … the editors and authors are to be commended for producing a well-organised, authoritative and succinct coverage of the vast area of gene therapy protocols. The materials are relevant, easy-to-follow and well-presented with good illustrations. Without doubt it will serve as a useful resource for those interested in this field, both scientists and clinicians … .”­­­ (Han Hsi Wong and Yaohe Wang, Human Genetics, Vol. 128, July, 2010)

Table of contents (35 chapters)

  • The Development of Gene Therapy: From Monogenic Recessive Disorders to Complex Diseases Such as Cancer

    Gillet, Jean-Pierre (et al.)

    Pages 5-54

  • Designing Adenoviral Vectors for Tumor-Specific Targeting

    Alemany, Ramon

    Pages 56-74

  • Analysis of HSV Oncolytic Virotherapy in Organotypic Cultures

    Fulci, Giulia (et al.)

    Pages 75-86

  • Use of Minicircle Plasmids for Gene Therapy

    Mayrhofer, Peter (et al.)

    Pages 87-104

  • Transposable Elements as Plasmid-Based Vectors for Long-Term Gene Transfer into Tumors

    Ohlfest, John R. (et al.)

    Pages 105-116

Buy this book

eBook $169.00
price for USA in USD (gross)
  • ISBN 978-1-59745-561-9
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $219.99
price for USA in USD
  • ISBN 978-1-934115-85-5
  • Free shipping for individuals worldwide
  • Online orders shipping within 2-3 days.
Softcover $219.99
price for USA in USD
  • ISBN 978-1-61737-946-8
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Loading...

Recommended for you

Loading...

Bibliographic Information

Bibliographic Information
Book Title
Gene Therapy of Cancer
Book Subtitle
Methods and Protocols
Editors
  • Wolfgang Walther
  • Ulrike S. Stein
Series Title
Methods in Molecular Biology
Series Volume
542
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-561-9
DOI
10.1007/978-1-59745-561-9
Hardcover ISBN
978-1-934115-85-5
Softcover ISBN
978-1-61737-946-8
Series ISSN
1064-3745
Edition Number
2
Number of Pages
XIV, 738
Number of Illustrations
89 b/w illustrations, 8 illustrations in colour
Topics