Methods in Molecular Biology

Neuroproteomics

Methods and Protocols

Editors: Ottens, Andrew K., Wang, Kevin K.W. (Eds.)

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  • Presents a modular approach to experimental design
  • Covers neurodegenerative models, subproteome selection technologies, quantitative and qualitative mass spectrometry, data analysis and clinical translation of results
  • Detailed guide to developing, running and analyzing broadly applicable neuroproteomic experiments
  • Provides specifics and insight to perform the latest quantitative and subproteome analyses, including key post-translational modifications
  • Examines a wide range of model systems used in neuroproteomic research, including ischemia, brain and spinal cord injury, substance abuse and neurodegenerative disease
  • Expands beyond the lab bench in providing guidance on translating neuroproteomic results to the clinic
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eBook $139.00
price for USA in USD
  • ISBN 978-1-59745-562-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $179.99
price for USA in USD
About this book

With the development of polypeptide ionization processes for mass spectrometry and the rapid processing of large-scale datasets with bioinformatics, researchers now have the tools necessary to propel neuroproteomics research to new levels. In Neuroproteomics: Methods and Protocols, experts in the neurological and analytical sciences present experimental details for applying proteomics to the study of the central nervous system (CNS) and its dysfunction through trauma and disease. Divided into four convenient sections, this collection covers CNS animal models used for neuroproteomics research, methods for separating and analyzing discrete subcomponents of the neuroproteome, large-scale approaches for CNS proteome characterization and quantification, as well as methods that evaluate biofluids and translate neuroproteomic results into clinical platforms. As a volume in the highly successful Methods in Molecular Biology™ series, chapters include brief introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and notes on troubleshooting and avoiding known pitfalls.

Authoritative and cutting-edge, Neuroproteomics: Methods and Protocols includes the clear "how-to" information needed to critically assess what can be accomplished in the field and how to best perform and evaluate neuroproteomic experiments in one’s own research.

Reviews

From the reviews: “This book provides experimental details about animal models for neuroproteomic research, methods for separating and analyzing discrete subcomponents of the neuroproteome, and CNS proteome characterization and quantification, as well as methods that evaluate biofluids and translate neuroproteomic results into clinical platforms. … The authors intend the book for basic and clinical researchers, and it will be of much interest to basic scientists, clinical scientists, and students interested in applying proteomics to the neurosciences.” (Omer Iqbal, Doody’s Review Service, March, 2010)

Table of contents (20 chapters)

Table of contents (20 chapters)

Buy this book

eBook $139.00
price for USA in USD
  • ISBN 978-1-59745-562-6
  • Digitally watermarked, DRM-free
  • Included format: EPUB, PDF
  • Immediate eBook download after purchase and usable on all devices
  • Bulk discounts available
Hardcover $219.99
price for USA in USD
Softcover $179.99
price for USA in USD
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Bibliographic Information

Bibliographic Information
Book Title
Neuroproteomics
Book Subtitle
Methods and Protocols
Editors
  • Andrew K. Ottens
  • Kevin K.W. Wang
Series Title
Methods in Molecular Biology
Series Volume
566
Copyright
2009
Publisher
Humana Press
Copyright Holder
Humana Press
eBook ISBN
978-1-59745-562-6
DOI
10.1007/978-1-59745-562-6
Hardcover ISBN
978-1-934115-84-8
Softcover ISBN
978-1-61779-754-5
Series ISSN
1064-3745
Edition Number
1
Number of Pages
XI, 321
Number of Illustrations
51 b/w illustrations
Topics