Handbook of Pediatric Cardiovascular Drugs

1. Front Matter

   Pages i-xiii

   PDF

2. Cardiac Physiology Review

   • Brian Feingold, Ricardo Munoz

   Pages 1-16

3. Clinical Pharmacokinetics: Applications in Pediatric Practice

   • Denise L. Howrie, Carol G. Schmitt

   Pages 17-32

4. Inotropic and Vasoactive Drugs

   • Eduardo da Cruz, Peter C. Rimensberger

   Pages 33-76

5. Vasodilators

   • Stephen J. Roth, Ricardo Munoz, Carol G. Schmitt, Eduardo da Cruz, Jonathan Kaufman, Cécile Tissot

   Pages 77-119

6. Diuretic Medications

   • Donald Berry, Traci M. Kazmerski

   Pages 120-138

7. β-Blockers

   • Constantinos Chrysostomou, Traci M. Kazmerski

   Pages 139-149

8. Antiarrhythmic Medications

   • Anne M. Dubin

   Pages 150-189

9. Immunosuppressive Agents in Pediatric Heart Transplantation

   • Indira A. Khimji, Traci M. Kazmerski, Steven A. Webber

   Pages 190-214

10. Extracorporeal Membrane Oxygenation and Drug Clearance

    • Peter D. Wearden, Victor O. Morell, Ricardo Munoz

    Pages 215-225

11. Pharmacological Treatment of Pulmonary Hypertension

    • Mary P. Mullen, David L. Wessel

    Pages 226-247

12. Anticoagulants, Antithrombotics, and Antiplatelets

    • Phuong-Tan Nguyen, Jessica Erin Sandy, Ricardo Munoz

    Pages 248-279

13. Sedative Hypnotic and Anesthetic Agents: Their Effect on the Heart

    • Charles I. Yang, Pravin Taneja, Peter J. Davis

    Pages 280-317

14. Drug Therapy for Hypercholesterolemia and Dyslipidemia

    • Sarah D. de Ferranti

    Pages 318-333

15. Medication Errors in Children

    • Robert L. Poole

    Pages 334-342

16. Back Matter

    Pages 343-356

    PDF

The treatment of pediatric patients with congenital or acquired cardiac disease remains an important challenge for physicians in charge of these often p- carious patients. It is well known that most of the drugs used in this field are either unlicensed or off-label. We have to face a very heterogeneous group of patients not only in pathologies but also in size, weight, and metabolism, p- ticularly when we face problems in premature or newborns. Not only have very few studies offered evidenced-based data for our pediatric patients, but even simple pharmacokinetics data are lacking. This is, to a great extent, caused by the difficulties of conducting research in pediatrics, particularly large-scale double-blinded randomized and controlled studies. This may change in the close future as authorities throughout the world have clearly stated that they will support this type of study. However, for the time being, we must rely on the available pharmacological knowledge, on the rare clinical trials and case series, and, most of all, on the international cumulative clinical experience. This comprehensive handbook on pediatric cardiovascular drugs offers a wide source of useful information for specialists in different fields, such as pediatricians, pediatric cardiologists, intensivists, neonatologists, anesthe- ologists, cardiac surgeons, nurses, and others involved in the management of cardiovascular disorders. It presents the updated knowledge and experience regarding the use of the currently available therapies for pediatric patients with primary or secondary cardiac and circulatory disorders.

• Carol G. Vetterly
• Pediatric
• cardiovascular
• hypertension
• physiology
• transplantation

From the reviews:

"Handbook of Pediatric Cardiovascular Drugs … may be a book that those individuals who touch pediatric patients with cardiovascular disease may want to take a close look at. … will be most valuable for the many adjunct members of the healthcare team who are not terribly familiar with the terrain covered with this book. … For those healthcare workers who like a book in their pocket rather than using on-line sources for their information, this handbook will serve as a fine addition to one’s collection." (Charles L. Schleien, Pediatric Critical Care Medicine, Vol 9 (6), 2008)

• Children's Hospital of Pittsburgh of UPMC, Pittsburgh, USA

  Ricardo Munoz, Carol G. Schmitt

• Stanford University School of Medicine, Palo Alto, USA

  Stephen J. Roth

• Children's University Hospital of Geneva, Switzerland

  Eduardo Cruz

Policies and ethics