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Investigative Electrocardiography in Epidemiological Studies and Clinical Trials

Authors: Rautaharju, Pentti, Rautaharju, Farida

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  • ISBN 978-1-84628-481-6
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Hardcover $249.99
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  • ISBN 978-1-84628-465-6
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Softcover $249.99
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  • ISBN 978-1-4471-5962-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
About this book

Electrocardiology is a relatively new modality in clinical trials, but electrocardiograms (ECGs) have already become established as a valuable research tool for investigation of morbidity and mortality risk associated with various clinical and subclinical conditions. ECGs have also become a crucial tool when investigating adverse cardiac events associated with administration of new drugs.

Investigative Electrocardiography in Epidemiological Studies and Clinical Trials reviews the prevalence and incidence and emphasizes the prognostic implications of common ECG abnormalities in contrasting populations. It provides a comprehensive, penetrating and critical analysis of topics such as QT prolongation in clinical drug trials, left ventricular hypertrophy, myocardial ischemia/infarction and epidemiological consideration of relative risks associated with ECG abnormalities. As such it is an essential tool in epidemiological or clinical research using ECGs and in investigations of possible adverse responses of new pharmacological agents.

With emphasis on providing international coverage of the topic, the well-respected authors present key information on ECG procedures, epidemiology, problem areas, mortality and morbidity risk. These topics are of particular interest to electrocardiologists, investigators in active ECG research in medical clinics participating in clinical trials, epidemiologists, cardiologists, pharmaceutical companies and regulatory bodies.

About the authors

The authors have closely collaborated for over a quarter of a Century in operating an academic ECG Center that has been in charge of ECG analysis of all major national health surveys conducted by the US National Center for Health Statistics, a series of large cardiovascular observational studies and clinical trials conducted by the US National Heart, Lung, and Blood Institute and several large clinical trials sponsored by pharmaceutical industry.

Reviews

From the reviews:

"This book reviews common ECG abnormalities in various populations and focuses on the prevalence and incidence of these abnormalities as well as the prognostic implications of the findings. It uniquely provides an extensive series of tables listing normal standard of ECG intervals, amplitudes, and vectors in various populations … . Investigators using electrocardiography as a research tool are the intended audience … . This is a thorough book that will be useful to its targeted audience." (Marc N. Saad, Doody’s Review Service, August, 2008)


Table of contents (21 chapters)

Table of contents (21 chapters)
  • Cardiac Excitation and Repolarization

    Pages 3-17

  • Electrocardiographic Lead Systems

    Pages 18-28

  • Normal and Arrhythmogenic Ionic Channel Mechanism

    Pages 29-44

  • Heart Rate and Heart Rate Variability

    Pages 45-67

  • Methodological Considerations in Heart Rate Variability Analysis

    Pages 68-73

Buy this book

eBook $189.00
price for USA in USD (gross)
  • ISBN 978-1-84628-481-6
  • Digitally watermarked, DRM-free
  • Included format: PDF
  • ebooks can be used on all reading devices
  • Immediate eBook download after purchase
Hardcover $249.99
price for USA in USD
  • ISBN 978-1-84628-465-6
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
Softcover $249.99
price for USA in USD
  • ISBN 978-1-4471-5962-9
  • Free shipping for individuals worldwide
  • Usually dispatched within 3 to 5 business days.
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Bibliographic Information

Bibliographic Information
Book Title
Investigative Electrocardiography in Epidemiological Studies and Clinical Trials
Authors
Copyright
2007
Publisher
Springer-Verlag London
Copyright Holder
Springer-Verlag London
eBook ISBN
978-1-84628-481-6
DOI
10.1007/978-1-84628-481-6
Hardcover ISBN
978-1-84628-465-6
Softcover ISBN
978-1-4471-5962-9
Edition Number
1
Number of Pages
X, 289
Topics